Displaying 584 (all) recruiting clinical trials.
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ZEUS - Effects of ziltivekimab versus placebo on cardiovascular outcomes in participants with established atherosclerotic cardiovascular disease chronic kidney disease and systemic inflammation
ZEUS - Effects of ziltivekimab versus placebo on cardiovascular outcomes in participants with established atherosclerotic cardiovascular disease, chronic kidney disease and systemic inflammation -
Randomized placebo controlled trial to determine the biological signature of cannabidiol as a treatment for social anxiety disorder
The goals of these two phased studies (“R61” followed by “R33”) are to establish a biological signature of CBD’s putative therapeutic effects in SAD ... -
The role of exercise in the consolidation of fear extinction learning in adults with high anxiety sensitivity
This is an experimental study (not a treatment study) aiming to examine the effects of acute exercise (vs. seated control) on fear extinction learning in ... -
A Multicenter Interventional Post-marketing Randomized Double-blind Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport ) in Comparison with OnabotulinumtoxinA (Botox ) when Treating Adults with Upper Limb Spasticity
The safety and efficacy of onabotulinumtoxinA (onaBoNT-A) and abobotulinumtoxinA (aboBoNT-A) have been investigated and demonstrated in phase III trials versus placebo. However, although both products ... -
LONG-TERM FOLLOW-UP STUDY OF PATIENTS WITH SPINAL MUSCULAR ATROPHY RECEIVING RISDIPLAM TREATMENT
This study will evaluate the long-term safety and effectiveness of risdiplam (Evrysdi?), prescribed on the basis of the U.S. Package Insert (USPI) and clinician ... -
A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence with Inflammatory Bowel DiSease Therapy ASSIST Study
The proposed study is a multicenter, randomized, controlled, clinical trial to be conducted over 12 months. Participants in the intervention arm will verify medication adherence ... -
Non-Invasive Salivary Biomarkers in Full Term Neonates
Despite modern advances that have greatly improved the health outcomes for infants, the field of neonatology still lacks reliable prognostic tools for many disorders. Non-invasively-obtained ... -
Endothelial Activation in Gout: Early Markers for Cardiovascular Risk
Gout, the most common inflammatory arthritis, is associated with accelerated rates of cardiovascular disease (CVD) and CVD-associated mortality. My group has shown that gout patients ... -
ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ... -
A phase 1 study of SGN-BB228 in advanced melanoma and other solid tumors
A phase 1 study of SGN-BB228 in advanced melanoma and other solid tumors