Displaying 597 (all) recruiting clinical trials.
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Proactive infliximab optimization using a pharmacokinetic dashboard versus standard of care in patients with Crohn s disease: The OPTIMIZE Trial
The purpose of this study is to find out if using a computer program (called iDose) to guide infliximab dosing is more effective and safer ...Phase N/A
Interventional
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A Telehealth tDCS Approach to Decrease Cannabis Use: Towards Reducing Multiple Sclerosis Disability
The purpose of this study is to determine if transcranial direct current stimulation, or tDCS, can be used to treat cannabis use disorder (CUD) in ...Phase
Interventional
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A Phase 3 Randomized Double-blind Study of Adjuvant Immunotherapy with Relatlimab and Nivolumab Fixed-dose Combination versus Nivolumab Monotherapy after Complete Resection of Stage III-IV Melanoma
The purpose of the study is to compare the effectiveness, safety, and toxicity of two treatments: relatlimab and nivolumab vs nivolumab monotherapy in participants with ...Phase
Interventional
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A Phase II Study of Pembrolizumab Plus Fulvestrant in Hormone Receptor Positive HER-2 Negative Advanced/Metastatic Breast Cancer Patients: Big Ten Cancer Research Consortium BTCRC-BRE16-042
The purpose of the study is to evaluate the anti-tumor activity of pembrolizumab with fulvestrant for subjects with metastatic, hormone receptor positive, HER2 negative breast ...Phase
Interventional
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Promoting adherence in upper extremity home-based rehabilitation through motivational interviewing and ecological momentary assessment: A mixed methods feasibility study
The purpose of this research study is to determine the pros and cons of delivering a new arm training program completed in the participants’ homes ...Phase N/A Interventional
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A Phase 1/2 Study of the Highly Selective EGFR Inhibitor BLU-701 in Patients with EGFR-Mutant Non-Small Cell Lung Cancer
The purpose of the study is to determine the overall safety of the study drug BLU-701, as assessed by the type, frequency, severity, timing, and ...
Phase
Interventional
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Induction Optimization with Stelara for Crohn s Disease
The purpose of this study is to compare the effectiveness of a second weight based dose of Stelara given intravenously to the standard dose administered ...Phase
Interventional
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A Phase 1/2a Multi-Center Open-Label Study to Evaluate the Safety Tolerability Pharmacokinetics and Preliminary Evidence of Antitumor Activity of JAB-3312 in combination with pembrolizumab or binimetinib in Adult Patients with Advanced Solid Tumors
The purpose of the study is to determine and demonstrate the safety and tolerability of JAB-3312 in combination with anti-PD-1 or MEKi in patients with ...Phase
Interventional
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A Phase 2/3 Randomized Open-Label Study of Maintenance GRT-C901/GRT-R902 A Neoantigen Vaccine in Combination with Immune Checkpoint Blockade for Patients with Metastatic Colorectal Cancer
The purpose of the study is to demonstrate clinical efficacy and characterize the clinical activity relating to the maintenance therapy with GRT-C901/GRT-R902 in combination ...Phase
Interventional
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A Phase 1a/1b Study of LY3537982 in Patients with KRAS G12C-Mutant Advanced Solid Tumors
The purpose of the study is to determine and evaluate the safety, tolerability, and preliminary efficacy of oral LY3537982 as monotherapy and as part of ...Phase
Interventional
