Displaying 690 (all) recruiting clinical trials.
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A Longitudinal Prospective Observational Study of the Characteristics Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States
The purpose of this study is to collect information to help us understand how doctors treat and manage people with severe asthma and how the ... -
AALL1731: A Phase 3 Trial Investigating Blinatumomab (IND# 117467 NSC# 765986) in Combination with Chemotherapy in Patients with Newly Diagnosed Standard Risk or Down syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients with Localized B-Lymphoblastic Lymphoma (B-LLy)
While outcomes in SR B-ALL have improved significantly, this population still accounts for approximately half of the overall burden of relapse among children with ALL ... -
Magnetic Resonance Imaging of Brain Reorganization and Sensory Substitution Use in Blind Adults
This research aims to examine how using certain types of visual assistive technology can influence behavior and brain activity in visually impaired individuals. The technology ... -
NN8640-4245 - A dose-finding trial evaluating the effect and safety of once-weekly treatment of somapacitan compared to daily Norditropin in children with short stature born small for gestational age with no catch-up growth by 2 years of age or older
This research study involves children born small and who stayed small. Treatment is somapacitan once a week compared to Norditropin® once a day. Researchers will ... -
Combined Craniomaxillofacial and Upper Extremity Allotransplantation
The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allotransplantation on patients who have ... -
STRIDE: A Study of Patients with Lower Extremity Acute Limb Ischemia to Remove Thrombus with the Indigo Aspiration System
LE ALI (lower extremity acute limb ischemia) is a serious medical condition that occurs when you have a sudden loss of blood flow in the ... -
Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
The purpose of this study is to see how safe and effective an investigational device called Intrepid TMVR system is for mitral regurgitation. TMVR stands ... -
A Phase 3 Multicenter Open-Label Extension Trial of Oral RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis
The purpose of this study is to see whether ozanimod (RPC1063), (also referred to as the ‘study drug’), is safe and how well it works ... -
Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD)
Inflammatory Bowel Diseases (IBD) are treated with many different medications, none of which are 100% effective. One of the challenges of treating IBD is to ... -
Methotrexate and Cholesterol Transport Regulation: Impact of Treatment Regimen in Diabetes and Metabolic Syndrome Cardiovascular Inflammation
Cardiovascular Inflammation Reduction Trial (CIRT) sub-study will examine those who have had a heart attack or have documented multi-vessel disease and have either type 2 ...