Displaying 721 (all) recruiting clinical trials.
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Multi-center Prospective Single Position Spine Surgery Outcomes Registry
The purpose of this study is to systematically, prospectively compare fusion techniques for thoracolumbar spinal fusion patients and assess long-term patient outcomes and revision rates.Phase N/A
Non-Interventional
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Duration of Time After Knee Intra-articular Injection to Pain Relief
We will identify patients who undergo injections of corticosteroids, hyaluronic acid, or platelet rich plasma for relief of osteoarthritis of the knees. We will then ...Phase N/A Non-Interventional
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RELATIONSHIP BETWEEN SYNOVIAL FLUID BIOMARKERS IN ACL RECONSTRUCTED PATIENTS AND PROGRESSION OF OSTEOARTHRITIS
We will perform a cross-sectional study on 25 patients undergoing isolated ACL reconstruction (intact menisci and articular cartilage). We have previously obtained samples of synovial ...Phase N/A Non-Interventional
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Ultrasound Channel Data Analysis Using Advanced Analytics and Deep Learning
Through the collection and analysis of the ultrasound channel data using advanced analytics and deep learning will provide new information previously unavailable that may improve ...Phase N/A Non-Interventional
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Understanding CSF Clearance in Aging and Alzheimer s Brain Through Dynamic Sodium MRI
This study aim to determine: 1) how age affects CSF production, bulk flow, and drainage in the normal brain; 2) the impact of sleep on ...Phase N/A Non-Interventional
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Edwards EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy using a Novel Device Short Title: TRISCEND II Pivotal Trial
The objectives of this clinical study are to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system with OMT compared to ...Phase N/A
Interventional
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Trabecular Structure on Wrist MRI in Early Osteoporosis
Osteoporosis and its complications - specifically, fragility fractures - constitute an enormous medical, economical, and societal burden. This problem is best addressed by prevention, but an optimal ...Phase N/A Non-Interventional
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Multi-Center Prospective Cervical Radiculopathy and Myelopathy of Adult Surgical Patients
The objective of this study is to develop a clinical registry of patients diagnosed with cervical radiculopathy or cervical myelopathy over a 3 year period ...Phase N/A Interventional
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A PHASE 1/2 STUDY OF REGN5678 (ANTI-PSMAXCD28) WITH OR WITHOUT CEMIPLIMAB (ANTI-PD-1) IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER AND OTHER TUMORS ASSOCIATED WITH PSMA EXPRESSION
This is an open-label, phase 1/2, first-in-human (FIH) study evaluating safety, tolerability, PK, and anti-tumor activity of REGN5678 (anti- PSMAxCD28) alone and in combination ...Phase
Interventional
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Verbal Working Memory and Attention Remediation for Adults with Traumatic Brain Injury.
This project will examine if computerized cognitive remediation will improve working memory and attention in 25 adults with a brain injury and compared their cognitive ...Phase
Interventional
