Displaying 689 (all) recruiting clinical trials.
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Interventional randomized double-blind parallel-group placebo-controlled multi-centre study to assess the efficacy safety and tolerability of Lu AF82422 in patients with Multiple System Atrophy
The purpose of this study is to find out whether a potential new treatment, the investigational drug Lu AF82422, is safe and effective in people ...Phase
Interventional
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AHCRN Registry: Characterizing Patient Populations in the Adult Hydrocephalus Clinical Research Network (AHCRN)
The purpose of this research project is to develop a patient registry, or database, for data collected during routine medical care of patients with hydrocephalus ...Phase N/A
Non-Interventional
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Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease
The purpose of this study is to learn more about whether nebulized hypertonic saline can help improve symptoms and clearance of mycobacteria. Hypertonic saline (7 ...Phase N/A Interventional
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Assessment of immunological and vascular dysfunction in neuropsychiatric post-acute sequelae of SARS-CoV-2 (long COVID-19) using TSPO PET and MRI
The purpose of this study is to develop brain imaging (PET/MRI) techniques to accurately assess immune system and blood vessel dysfunction in the brain ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Prospective NIPT Sample Collection Protocol
The purpose of this study is to collect blood samples from volunteers to develop a new noninvasive prenatal test, that can detect these genetic abnormalities ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Predicting poor vaccine responders to Hepatitis B vaccination
The purpose of this study is to understand how the immune system learns from the hepatitis B vaccine and why some people do not respond ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 2 Study of BA3011 Alone and in Combination with Nivolumab in Adult Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) Who Had Prior Disease Progression on a PD-1/L-1 Inhibitor
The purpose of the study is designed to evaluate the efficacy and safety of BA3011 alone and in combination with nivolumab in patients with AXL-expressing ...Phase
Interventional
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Medtronic SMall Annuli Randomized To Evolut or Sapien Trial (SMART Trial)
The purpose of this study is to collect information and compare the safety and performance of self- expanding (SE) versus balloon-expandable (BE) transcatheter aortic valve ...Phase N/A Interventional
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Phase II Trial of Radium-223 Dichloride in Combination with Paclitaxel in Patients with Bone Metastatic Breast Cancer
The purpose of the study is to determine the safety and efficacy of the combination of Radium-223 dichloride and paclitaxel. We want to know if ...Phase
Interventional
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Goal-Directed Cardiopulmonary Resuscitation in Cardiac Arrest Using a Novel Physiological Target: A Pilot Mechanistic Randomized Control Trial
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological ...Phase
Interventional
