Displaying 716 (all) recruiting clinical trials.
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The PROGRESS Trial - Continued Access Study Number: 2021-01-CAP
The purpose of this study is to evaluate an investigational treatment for people with moderate, calcific aortic stenosis:
The SAPIEN 3, SAPIEN 3 Ultra, and ...Phase N/A
Interventional
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Effectiveness and impact of counseling enhanced with electronic cigarettes for harm reduction in smokers with opioid use disorder
We are conducting a research study to compare the effectiveness of telehealth counseling plus electronic cigarettes VERSUS telehealth counseling plus nicotine replacement therapy (patches and ...Phase
Interventional
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Master protocol of two independent randomized double-blind Phase 3 studies comparing efficacy and safety of frexalimab (SAR441344) to teriflunomide in adult participants with relapsing forms of multiple sclerosis.
This clinical trial aims to assess the effectiveness and safety of an investigational drug, frexalimab, for treating relapsing multiple sclerosis (RMS). Frexalimab works by targeting ...Phase
Interventional
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Genetic Investigations in Atrial Arrhythmias
The purpose of this study is to learn more about the reasons that people have abnormal rhythms in the top part of the heart (the ...Phase N/A
Non-Interventional
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Understanding Disease Burden in Biliary Atresia
It is our understanding that Biliary atresia (BA) can significantly affect a BA patient’s quality of life.? This study aims to assess the frequency ...Phase N/A Non-Interventional
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A Phase 1/2 First-Time-in-Human open-label multicenter dose escalation and expansion study of the oral DNA Helicase Werner Inhibitor (WRNi) GSK4418959 alone or in combination with other anti-cancer agents in adult participants with Mismatch Repair-deficient (dMMR) or Microsatellite Instability-High (MSI-H) solid tumors (SYLVER)
This study will test how well the oral WRN inhibitor GSK4418959 works and whether it has few side effects, both by itself and with dostarlimab ...
Phase
Interventional
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The Anti-Inflammatory Effects of Milk-Derived Extracellular Vesicles in Preterm Infant
The purpose of this study is to examine and compare Milk-Derived Extracellular Vesicles (EVs) in three types of milk: mothers' own milk, donor milk, and ...Phase N/A Non-Interventional
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A Transdiagnostic Study of Emotional Impulsivity in Suicidal Ideation and Behavior
The purpose of this research study is to understand and learn more about why some people with schizophrenia or depression are more likely to think ...Phase N/A Interventional
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Observational Study of Vedolizumab and Ustekinumab in Crohn's Disease Patients in Canada and the US
This is a real-world, multicenter, retrospective, observational, chart review study evaluating the outcomes of treatment with Vedolizumab (VDZ) and Ustekinumab (UST) in patients with Crohn ...Phase N/A Non-Interventional
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Collaborative Registry to Determine the Natural History of Barth Syndrome
The purpose of this research study is to collect data that we hope will help answer those questions and improve outcomes for children with Barth ...Phase N/A Non-Interventional
