Displaying 247 (all) recruiting clinical trials.
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MINERALOCORTICOID RECEPTOR ANTOGONISM IN ATHEROSCLEROSIS (MAGMA-ADDON)
Atherosclerotic disease, or hardening of the arteries, is characterized by the thickening of the arterial walls due to fatty deposits in wall and inflammation in ...Phase N/A
Interventional
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The AIM-HN and SEQ-HN Study: A 2 Cohort Non-comparative Pivotal Study Evaluating the Efficacy of Tipifarnib in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) with HRAS Mutations (AIM-HN) and the Impact of HRAS Mutations on Response to First Line Systemic Therapies for HNSCC (SEQ-HN)
The purpose of this research study is to see how effective the study drug is to treat your tumor. Other reasons for conducting the study ...Phase N/A Interventional
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Zoster Eye Disease Study (ZEDS): A multi-center randomized double-masked placebo-controlled clinical trial of suppressive valacyclovir for one year in immunocompetent study participants with an episode of dendriform epithelial keratitis stromal keratitis endothelial and/or iritis due to Herpes Zoster Ophthalmicus (HZO) in the year prior to enrollment
The purpose of this study is to find out whether one year of a low dose of the medicine valacyclovir reduces complications of shingles affecting ...Phase N/A Interventional
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Edwards PASCAL TrAnScatheter Mitral Valve RePair System Pivotal Clinical Trial (CLASP IID): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Mitral Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR)
The goal of this study is to assess the safety and performance of the PASCAL System in patients with symptomatic degenerative mitral regurgitation (DMR) who ...Phase N/A Interventional
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Measurement of Thrombelastography as an alternative means to guide blood product use before invasive procedures in cirrhosis with severe coagulopathy: An observational study
The purpose of this study is to test the use of a blood test known as thromboelastography (TEG). This study will help us see if ...Phase N/A
Non-Interventional
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A Prospective International Hip Dysplasia Registry with Follow-up to Skeletal Maturity: An Analysis of Risk Factors Screening Practices and Treatment Outcomes
The purpose of this study is to develop a general prospective registry that includes all elements of the DDH spectrum, from mild dysplasia of a ...Phase N/A Non-Interventional
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AWARE II (AWAreness during REsuscitation) - A Multi-Centre Observational Study of the Relationship between the Quality of Brain Resuscitation and Consciousness Neurological Functional and Cognitive Outcomes following Cardiac Arrest
The purpose of this study is to determine whether clinical measures to improve resuscitation in patients experiencing cardiac arrest (a stopped heart) leads to increased ...Phase N/A Non-Interventional
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Metabolomics of World Trade Center-Lung Injury: Biomarker Validation Assessment and Dietary Intervention Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
The purpose of this study is to determine if a low calorie Mediterranean (LoCalMed) type diet, or the “FIREHOUSE” diet, program helps to improve WTC-LI ...Phase N/A Non-Interventional
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Colchicine for the Treatment of Osteoarthritis of the Knee (CLOAK)
Osteoarthritis (OA) is a common, painful, and debilitating form of arthritis for which no cure currently exists. The purpose of this study is to determine ...Phase N/A Interventional
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Tissue Acquisition of Arterial Aneurysms
The purpose of the study is to study the mechanisms of the natural history of aneurysms and potential circulating biomarkers in your blood. An aneurysm ...Phase N/A Non-Interventional
