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Mechanisms of Vascular Aneurysms
Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention ... -
Genetic evaluation of patients with undiagnosed diseases
The purpose of this study is to use extensive sequencing of the DNA (genetic material inherited from parents) or RNA (transcripts of the DNA), and ... -
Impact of time restricted feeding in obese subjects undergoing a low-calorie diet
The impact of circadian rhythms appear to impact various biologic mechanisms including sleep, nutrition, and physical activity. We wish to understand the impact of timing ... -
Multicenter Study of Epilepsy Surgery Long Term Outcomes Mortality
The Multicenter Study of Epilepsy Surgery – Long Term Outcomes Mortality study aims to examine the various aspects of epilepsy surgery outcomes after more than 10 ... -
Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery?
The research design of this study is a prospective cohort study. Potential subjects will be any patients undergoing elective laparoscopic weight loss surgery including: gastric ... -
Quantitative Sodium MR Imaging and Proton MR Spectroscopy in Traumatic Brain Injury
The objectives of this study are to investigate new measures of TBI damage obtained from sodium Magnetic Resonance Imaging and to integrate sodium MRI with ... -
SWIFT TRIAL: SURGICAL WEIGHT-LOSS TO IMPROVE FUNCTIONAL STATUS TRAJECTORIES FOLLOWING TOTAL KNEE ARTHROPLASTY
We will compare long-term outcomes in the test and control arms of the study. These outcomes will include measures of physical function, mobility, indices of ... -
Cochlear implants and listening effort: the interaction of cognitive and sensory constraints
Hearing impairment is the third most prevalent chronic medical condition among older adults in the United States. Untreated, hearing loss can interfere with effective communication ... -
THE PROSPECTIVE NATURAL HISTORY OF FAMILIAL DYSAUTONOMIA
Our ultimate goal is to develop new treatments for patients with familial dysautonomia (FD, OMIM 223900). We also want to learn which specific nerve populations ... -
MICROBiome Involvement in Outcomes of Methotrexate Efficacy-RA
This is a prospective, observational, proof-of-principle, open-label, single-blinded study looking at the effects of the gut microbiome on the metabolism and response to methotrexate treatment ...