Displaying 47 (all) recruiting clinical trials.
-
A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Nivolumab will be investigated at the Food and Drug Administration (FDA)-approved dose of 480 mg intravenous (IV) every 4 weeks until unacceptable toxicity, disease ...Phase
Interventional
-
Personalizing sleep interventions to prevent type 2 diabetes in community dwelling adults with prediabetes: A phase 1 single center randomized clinical trial of the effects of improving sleep on glycemic control in participants with prediabetes
The proposed study will test the effects of a sleep intervention versus a control intervention on the percentage of time glucose is greater than or ...Phase
Interventional
-
Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity using Advanced Imaging Modality Arthroscopy: A Prospective Randomized Trial
Rotator cuff re-tear is a common delayed complication of arthroscopic rotator cuff repair. This process of re-tear is multifactorial and there has not been any ...Phase
Interventional
-
The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft
This study will compare 3 commonly used bone-void fillers, autologous bone, calcium phosphate cement, and demineralized bone matrix to fill the bony defect association with ...Phase
Interventional
-
Transcranial Photobiomodulation for Alzheimer's Disease
This multi-site study will be the first to evaluate the dose-dependent effects of t-PBM in amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease ...Phase
Interventional
-
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute LeukemiaPhase
Interventional
-
Pilot Randomized Controlled Trial of Integrated Supportive Care with Nephrology Care
This study is a pilot randomized controlled trial testing the feasibility of an integrated supportive care approach in the ambulatory setting in nephrology as well ...Phase
Interventional
-
Examining the Impact of Family Connectors
The purpose of this study is to examine the association between involvement in Family Connectors, a manualized peer-to-peer support and education program for family members ...Phase
Interventional
-
GUT KIDNEY AXIS IN ENTERIC HYPEROXALURIA - A clinical prospective study of the effects of the microbiome on urinary oxalate in participants with enteric hyperoxaluria fed a moderate oxalate diet
40 subjects with a confirmed diagnosis of IBD or >6 months post-RYGB with a diagnosed USD event or kidney stone on imaging within the past ...Phase
Interventional
-
A Phase 1/1b Open-label Multicenter Study to Investigate the Safety Tolerability Pharmacokinetics and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation-positive Solid Tumors
This is a 2-part, open-label, multicenter, dose escalation and dose expansion study in participants with rapidly accelerated fibrosarcoma, homolog B (BRAF) mutation-positive and/or neuroblastoma ...Phase
Interventional
