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Sleep and Prediabetes Project
The purpose of this research study is to compare the effects of individual counseling to improve sleep, eating habits, and physical activity versus individual counseling ...Phase
Interventional
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A Phase 1b First-in-Human Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b
The purpose of the study is to determine the safety and tolerability of the antibody-drug conjugate (ADC) XMT-1536 administered as an intravenous infusion once every ...Phase
Interventional
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Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity using Advanced Imaging Modality Arthroscopy: A Prospective Randomized Trial
The purpose of this study is to determine the optimal dosing of an injectable fluorescent pigment, Indocyanine Green (ICG), for use during rotator cuff surgeries ...Phase
Interventional
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A PHASE 1 OPEN-LABEL DOSE FINDING STUDY OF CC-95251 A MONOCLONAL ANTIBODY DIRECTED AGAINST SIRPa ALONE AND IN COMBINATION WITH CETUXIMAB OR RITUXIMAB IN SUBJECTS WITH ADVANCED SOLID AND HEMATOLOGIC CANCERS
The purpose of the study is to look at how your body tolerates CC-95251 and safety of the CC-95251 when administered intravenously (IV) as single ...Phase
Interventional
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A Phase 1 Open-label Multicenter Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of IGM-2323 in Subjects with Relapsed/Refractory Non-Hodgkin Lymphomas
The purpose of the study is to evaluate how your body tolerates IGM-2323, the safety of IGM-2323, and how IGM-2323 is taken up by your ...Phase
Interventional
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The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft
The purpose of this study is to evaluate the effect of and compare bone-void filler material on outcomes following anterior cruciate ligament (ACL) reconstruction with ...Phase
Interventional
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Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
The purpose of the trial is to determine the safety and tolerability of birinapant concurrent with intensity modulated re-irradiation therapy for patients who have Locoregionally ...Phase
Interventional
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Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
People with mild cognitive impairment (MCI) have more memory problems than normal for people their age, but their symptoms are not as severe as those ...Phase
Interventional
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A Phase 1 Study of RTX-321 for the Treatment of Patients with Advanced Malignancies Associated with Human Papillomavirus-16 Infection
The purpose of the study is to determine the safety and tolerability of RTX-321 for the treatment of patients that are HLA-A*02:01 (a ...Phase
Interventional
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An Open Label Phase 1 Dose-Escalation Study to Evaluate the Safety and Preliminary Antitumor Activity of TAK-676 with Pembrolizumab Following Radiation Therapy in the Treatment of Non-Small-Cell Lung Cancer Triple-Negative Breast Cancer or Squamous Cell Carcinoma of the Head and Neck that has Progressed on Checkpoint Inhibitors
The purpose of the study is to evaluate the safety, tolerability, and preliminary antitumor activity of TAK-676 and pembrolizumab following radiation therapy in the treatment ...Phase
Interventional
