Displaying 45 (all) recruiting clinical trials.
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A Phase 1 Open-Label Multicenter Study to Assess the Safety Tolerability and Immunogenicity of mRNA-4157 Alone in Subjects with Resected Solid Tumors and in Combination with Pembrolizumab in Subjects with Unresectable Solid Tumors
If you have been diagnosed with solid tumors, either removed previously by surgery or unresectable (locally advanced or metastatic), you may qualify for this phase ...Phase
Interventional
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A PHASE 1 STUDY OF PRE-OPERATIVE CEMIPLIMAB (REGN2810) ADMINISTERED INTRALESIONALLY FOR PATIENTS WITH RECURRENT CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
The main purpose of this study is to determine the safet and tolerability of cemiplimab. Cemiplimab-rwic is only approved by the U.S. Food and ...Phase
Interventional
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A Phase 1 Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants with Gastrointestinal Malignancies
The purpose of this study is to understand whether potential new drugs, AB680 and AB122, can be safely given to patients with pancreatic cancer in ...Phase
Interventional
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A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
We want to know the safety and tolerability of the anti-programmed death 1 (PD-1) antibody nivolumab at different dose levels for patients with autoimmune disorders ...Phase
Interventional
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Sleep and Prediabetes Project
The purpose of this research study is to compare the effects of individual counseling to improve sleep, eating habits, and physical activity versus individual counseling ...Phase
Interventional
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Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity using Advanced Imaging Modality Arthroscopy: A Prospective Randomized Trial
The purpose of this study is to determine the optimal dosing of an injectable fluorescent pigment, Indocyanine Green (ICG), for use during rotator cuff surgeries ...Phase
Interventional
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The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft
The purpose of this study is to evaluate the effect of and compare bone-void filler material on outcomes following anterior cruciate ligament (ACL) reconstruction with ...Phase
Interventional
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Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
People with mild cognitive impairment (MCI) have more memory problems than normal for people their age, but their symptoms are not as severe as those ...Phase
Interventional
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Verbal Working Memory and Attention Remediation for Adults with Traumatic Brain Injury.
The purpose of this study is to examine if cognition in individuals with moderate to severe traumatic brain injury can be improved. This project will ...Phase
Interventional
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A Phase 1 Open-label Preliminary Pharmacokinetics (PK) and Safety Study of CLN-049 (An fms-like tyrosine kinase 3 [FLT3] x cluster of differentiation 3 [CD3] bispecific T cell engager) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)
The purpose of the study is to determine the safety and tolerability of intravenous (IV) administered CLN-049. CLN-049 is a novel BITE therapy that target ...Phase
Interventional
