Displaying 51 (all) recruiting clinical trials.
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A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Nivolumab will be investigated at the Food and Drug Administration (FDA)-approved dose of 480 mg intravenous (IV) every 4 weeks until unacceptable toxicity, disease ...Phase
Interventional
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Personalizing sleep interventions to prevent type 2 diabetes in community dwelling adults with prediabetes: A phase 1 single center randomized clinical trial of the effects of improving sleep on glycemic control in participants with prediabetes
The proposed study will test the effects of a sleep intervention versus a control intervention on the percentage of time glucose is greater than or ...Phase
Interventional
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Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity using Advanced Imaging Modality Arthroscopy: A Prospective Randomized Trial
Rotator cuff re-tear is a common delayed complication of arthroscopic rotator cuff repair. This process of re-tear is multifactorial and there has not been any ...Phase
Interventional
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The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft
This study will compare 3 commonly used bone-void fillers, autologous bone, calcium phosphate cement, and demineralized bone matrix to fill the bony defect association with ...Phase
Interventional
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Transcranial Photobiomodulation for Alzheimer's Disease
This multi-site study will be the first to evaluate the dose-dependent effects of t-PBM in amnestic Mild Cognitive Impairment (aMCI) and early Alzheimer’s Disease ...Phase
Interventional
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute LeukemiaPhase
Interventional
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Pilot Randomized Controlled Trial of Integrated Supportive Care with Nephrology Care
This study is a pilot randomized controlled trial testing the feasibility of an integrated supportive care approach in the ambulatory setting in nephrology as well ...Phase
Interventional
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Examining the Impact of Family Connectors
The purpose of this study is to examine the association between involvement in Family Connectors, a manualized peer-to-peer support and education program for family members ...Phase
Interventional
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GUT KIDNEY AXIS IN ENTERIC HYPEROXALURIA - A clinical prospective study of the effects of the microbiome on urinary oxalate in participants with enteric hyperoxaluria fed a moderate oxalate diet
40 subjects with a confirmed diagnosis of IBD or >6 months post-RYGB with a diagnosed USD event or kidney stone on imaging within the past ...Phase
Interventional
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A Phase 1 First in human Dose Escalation and Expansion Multicenter Study of XMT-1660 in Participants with Solid Tumors
The proposed first-in-human study of XMT-1660 will be a Phase 1, open-label trial of XMT-1660 in previously treated participants with metastatic TNBC, HR+/HER2- or ...Phase
Interventional
