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A PHASE 1 STUDY OF PRE-OPERATIVE CEMIPLIMAB (REGN2810) ADMINISTERED INTRALESIONALLY FOR PATIENTS WITH RECURRENT CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
The main purpose of this study is to determine the safet and tolerability of cemiplimab. Cemiplimab-rwic is only approved by the U.S. Food and ...Phase
Interventional
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Phase 1/1b Study to Evaluate the Safety & PK of JNJ-73841937 a Third Generation EGFR-TKI as Monotherapy or in Combinations With JNJ-61186372 a Human Bispecific EGFR and cMet Antibody in Participants With Advanced NSCLC
The purpose of the study is to determine the safety and tolerability of JNJ-73841937 (Lazertinib), a Third Generation EGFR-TKI, as Monotherapy or in Combinations With ...Phase
Interventional
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A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
We want to know the safety and tolerability of the anti-programmed death 1 (PD-1) antibody nivolumab at different dose levels for patients with autoimmune disorders ...Phase
Interventional
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Sleep and Prediabetes Project
The purpose of this research study is to compare the effects of individual counseling to improve sleep, eating habits, and physical activity versus individual counseling ...Phase
Interventional
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Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity using Advanced Imaging Modality Arthroscopy: A Prospective Randomized Trial
The purpose of this study is to determine the optimal dosing of an injectable fluorescent pigment, Indocyanine Green (ICG), for use during rotator cuff surgeries ...Phase
Interventional
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The Effect of Bone-void filler on Anterior Knee Pain Following ACL Reconstruction with Bone-Patellar Tendon Bone Autograft
The purpose of this study is to evaluate the effect of and compare bone-void filler material on outcomes following anterior cruciate ligament (ACL) reconstruction with ...Phase
Interventional
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Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
The purpose of the trial is to determine the safety and tolerability of birinapant concurrent with intensity modulated re-irradiation therapy for patients who have Locoregionally ...Phase
Interventional
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Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
People with mild cognitive impairment (MCI) have more memory problems than normal for people their age, but their symptoms are not as severe as those ...Phase
Interventional
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Scaling Telehealth Models to Improve Co-morbid Diabetes and Hypertension in Immigrant Populations
The purpose of this study is to work with primary care physicians and their staff, and with community health workers (CHWs) to improve diabetes and ...Phase
Interventional
Accepts Healthy Volunteer
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Verbal Working Memory and Attention Remediation for Adults with Traumatic Brain Injury.
The purpose of this study is to examine if cognition in individuals with moderate to severe traumatic brain injury can be improved. This project will ...Phase
Interventional
