Displaying 58 (all) recruiting clinical trials.
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A First in Human Study of theMenin-KMT2A (MLL1)Inhibitor JNJ-75276617 in Participants with Acute Leukemia
The primary objectives of this study are to determine the recommended phase 2 dose(s) (RP2Ds) of JNJ-75276617, as well as the safety and tolerability ...Phase
Interventional
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A Phase I First-In-Human Multicenter Open-Label Study of Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors
The purpose of the study is to determine the safety, tolerability, and immunogenicity, and to detect any preliminary evidence of anti-tumor activity of Nous-209 genetic ...Phase
Interventional
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Reach Out Stay Strong Essentials for mothers of newborns (ROSE) Adaptation for Chinese American mothers
The study is a cultural adaptation and pilot study of a postpartum depression prevention intervention among pregnant Chinese American women. The study consists of focus ...Phase
Interventional
Accepts Healthy Volunteer
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A Pilot Randomized Controlled Trial of Integrated Supportive and Nephrology Care versus Usual Care
The purpose of this study is to test the impact of adding a form of care known as palliative, or supportive, care to your usual ...Phase
Interventional
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Examining the Impact of Family Connectors
The purpose of this study is to understand the impact of Family Connectors, a peer-to-peer support and education program for family members who have participated ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 1b Multicenter Study to Determine the Dose Safety Efficacy and Pharmacokinetics of TRK-950 when Used in Combinations with Selected Anti-Cancer Treatment Regimens in Patients with Selected Advanced Solid Tumors.
The purpose of the study is to evaluateTRK-950 in combination with 1) FOLFIRI or 2) Gemcitabine / Cisplatin or 3) Gemcitabine / Carboplatin or 4) Ramucirumab/Paclitaxel ...Phase
Interventional
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A Phase 1a/1b Study of LY3537982 in Patients with KRAS G12C-Mutant Advanced Solid Tumors
The purpose of the study is to determine and evaluate the safety, tolerability, and preliminary efficacy of oral LY3537982 as monotherapy and as part of ...Phase
Interventional
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Gut Kidney Axis in Enteric Hyperoxaluria
The purpose of this research study is to study the effects of enteric hyperoxaluria (EH) when they are given a pre-prepared diet. EH is a ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase 1b First-in-human Dose Escalation and Expansion Multicenter Study of XMT-1660 in Participants with Solid Tumors
If you are diagnosed with stage 4 tumor of any solid origin, for example; breast, endometrial, ovarian, fallopian tube, cervix, vaginal or primary peritoneal cancer ...
Phase
Interventional
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Optimized MRI of patients with hip arthroplasty
In patients with hip replacement, the metal of the artificial hip darkens the magnetic resonance imaging (MRI) images which is called shadowing. The purpose of ...Phase
Interventional
