Displaying 103 (all) recruiting clinical trials.
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Randomized Phase 2 Study of Erdafitinib vs Investigator Choice of Chemo in Subjects Who Received BCG and Recurred With HR NMIBC (42756493BLC2003)
The purpose of the study is to determine the safety and efficacy of erdafitinib in subjects with Non-Muscle-Invasive Bladder Cancer (NMIBC) and fibroblast growth factor ...Phase
Interventional
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A Phase 2 Study to Evaluate the Efficacy and Safety of Pembrolizumab plus Investigational Agents in Combination with Etoposide and Cisplatin or Carboplatin for the First-Line Treatment of Participants with Extensive-Stage Small Cell Lung Cancer (KEYNOTE-B99)
The purpose of the study is to determine the efficacy and safety of Pembrolizumab plus investigational Agents in combination with etoposide and Cisplatin or Carboplatin ...Phase
Interventional
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A Telehealth tDCS Approach to Decrease Cannabis Use: Towards Reducing Multiple Sclerosis Disability
The purpose of this study is to determine if transcranial direct current stimulation, or tDCS, can be used to treat cannabis use disorder (CUD) in ...Phase
Interventional
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A Phase II Study of Pembrolizumab Plus Fulvestrant in Hormone Receptor Positive HER-2 Negative Advanced/Metastatic Breast Cancer Patients: Big Ten Cancer Research Consortium BTCRC-BRE16-042
The purpose of the study is to evaluate the anti-tumor activity of pembrolizumab with fulvestrant for subjects with metastatic, hormone receptor positive, HER2 negative breast ...Phase
Interventional
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A Phase 2 randomized open-label three-arm clinical study to evaluate the safety and efficacy of lenvatinib (E7080/MK-7902) in combination with pembrolizumab (MK-3475) versus standard of care chemotherapy and lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) that have progressed after platinum therapy and immunotherapy (PD-1/PD-L1 inhibitors) (LEAP-009)
The purpose of the study is to evaluate the safety and efficacy of Lenvatinib with or without pembrolizumab versus standard of care chemotherapy, for previously ...Phase
Interventional
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Induction Optimization with Stelara for Crohn s Disease
The purpose of this study is to compare the effectiveness of a second weight based dose of Stelara given intravenously to the standard dose administered ...Phase
Interventional
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Autologous Intraarticular Micro-Fragmented Adipose Transfer
The purpose of this study is to determine if transferring fat tissue from your lower abdomen or outer thigh into the base of the thumb ...Phase
Interventional
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A Phase II Study to Evaluate the Efficacy and Safety of GT90001 in Combination with Nivolumab as a Second-line Treatment in Subjects with Advanced Hepatocellular Carcinoma
The purpose of the study is to examine and assess the antitumor activities of Nivolumab in combination with GT90001 or Nivolumab alone in subjects with ...
Phase
Interventional
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A Phase 2 Randomized Double-Blind Placebo-Controlled Efficacy and Safety Study of VIB7734 for the Treatment of Moderate to Severely Active Systemic Lupus Erythematosus
The purpose of this study is to learn how well VIB7734 is tolerated in patients with SLE, to determine if it causes any side effects ...Phase
Interventional
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A Multi-Center Randomized Double-blind Placebo-controlled Dose-finding Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CK-3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy
Some people with HCM have obstructive HCM (oHCM) and other participants have non-obstructive HCM (nHCM). HCM is a condition in which the heart muscle becomes ...Phase
Interventional
