Displaying 85 (all) recruiting clinical trials.
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A Randomized Double-blind Placebo-controlled Phase 2a Study to Evaluate the Safety and Efficacy of Zetomipzomib (KZR-616) in Patients with Autoimmune Hepatitis
This is a Phase 2a, multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and efficacy of zetomipzomib in patients with AIH who have ... -
RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED PHASE 2 STUDY OF VE202 IN PATIENTS WITH MILD-TO-MODERATE ULCERATIVE COLITIS
This is a phase 2 double-blind, placebo-controlled, randomized study to evaluate the safety, efficacy, and microbiota changes of VE202 in biologic-naïve patients with mild to ... -
A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Volixibat in the Treatment of Cholestatic Pruritus in Patients with Primary Sclerosing Cholangitis (VISTAS)
The purpose of this clinical research study is to learn more about the use of the study drug, volixibat, for the treatment of pruritus (itching ... -
A Phase 2 Multicenter Randomized Double-blind Placebo-controlled Study to Evaluate the Safety Tolerability Pharmacokinetics and Efficacy of TTI-101 in Participants with Idiopathic Pulmonary Fibrosis
This multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical study is designed to evaluate the safety and tolerability of 3 dose levels of TTI-101 vs placebo in ... -
A Phase II multicenter open-label single-arm dose escalation study of Asciminib monotherapy in 2nd and 1st Line Chronic Phase Chronic Myelogenous Leukemia (ASC2ESCALATE)
This study involves two groups of people with a type of blood cancer called chronic myeloid leukemia in its early stage. In one group, there ...
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E-cigarettes for Harm Reduction Among Smokers with Serious Mental Illness
The purpose of this research study is to compare the effectiveness of electronic cigarettes and telehealth counseling versus nicotine replacement therapy (patches, lozenges and gum ... -
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
The purpose of this double-blind randomized study is to explore the efficacy of psilocybin (5-HT2A receptor agonist psilocybin) as a smoking cessation treatment. In this ...
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AbbVie M21-446 - A Single-Arm Open-Label Study to Evaluate the Efficacy and Safety of ABBV-668 in Subjects With Moderate to Severe Ulcerative Colitis
The purpose of this study is to see if the study drug called ABBV-668 is safe and effective at treating moderate to severe ulcerative colitis. -
A Phase 2 Randomized Study to Evaluate the Optimized Dose Safety and Efficacy of Livmoniplimab in Combination with Budigalimab for Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Patients who Have Progressed After an Immune Checkpoint Inh
This research study aims to find out if two medicines, livmoniplimab (a special drug used to boost the body's ability to fight liver cancer ...
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Brightline-2: A Phase IIa/IIb open-label single-arm multi-centre trial of BI 907828 for treatment of patients with locally advanced / metastatic MDM2 amplified TP53 wild-type biliary tract adenocarcinoma pancreatic ductal adenocarcinoma or other se
The purpose of the trial is to study a drug called BI 907828 for the treatment of certain types of advanced or spreading tumors. These ...