Displaying 104 (all) recruiting clinical trials.
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A Randomized 3-Arm Phase II Study Comparing 1.) Bendamustine Rituximab and High Dose Cytarabine (BR/CR) 2.) Bendamustine Rituximab High Dose Cytarabine and Acalabrutinib (BR/CR-A) and 3.) Bendamustine Rituximab and Acalabrutinib (BR-A) in Patients = 70 years old with Untreated Mantle Cell Lymphoma
The purpose of the study is to determine the efficacy and tolerability of bendamustine (B), rituximab (R) and high dose cytarabine (C) [(BR/CR] versus ...Phase
Interventional
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INTREPId (INTermediate Risk Erection PreservatIon Trial): A Randomized Trial of Radiation Therapy and Darolutamide for Prostate Cancer
The purpose of the trial is to determine whether Darolutamide plus radiation therapy (RT) is non-inferior to gonadotropin releasing hormone (GnRH) agonist and bicalutamide plus ...Phase
Interventional
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A Basket Trial of Pembrolizumab in Patients with Advanced Solid Tumors and Genomic Instability
The purpose of the study is to evaluate the response rate of pembrolizumab in patients with evidence of genomic instability classified as follows: 1) All ...Phase
Interventional
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Site for 10144 - A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma with DNA-Repair Defects
The purpose of the study is to determine if olaparib works in treating patients with urothelial cancer with deoxyribonucleic acid (DNA)-repair defects that has ...Phase
Interventional
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Abaloparatide versus Placebo for Pelvic Fracture Healing - A Phase 2 Randomized Controlled Trial
The purpose of this study is to determine whether Abaloparatide, also known as Tymlos can help to heal a broken bone (fracture) in the pelvis ...Phase
Interventional
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A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of DCR-PHXC in Patients With Primary Hyperoxaluria Type 1 or 2 and Severe Renal Impairment With or Without Dialysis
The purpose of this study is to learn whether the study drug DCR-PHXC is safe and able to treat patients with Primary Hyperoxaluria Type 1 ...Phase
Interventional
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A Phase IIa Open-label Clinical Trial to Evaluate the Safety Pharmacokinetics Pharmacodynamics and Efficacy of BP1001 (a Liposomal Grb2 Antisense Oligonucleotide) in Combination with Venetoclax plus Decitabine in Patients with Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Induction Therapy
The first purpose of this study is to learn if combining the study drug BP1001 with the standard-of-care drugs Venetoclax and decitabine in first line ...Phase
Interventional
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Multicenter Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy Safety and Tolerability of 36 weeks of treatment with NLY01 in Early-Stage Parkinson s Disease
Parkinson’s disease is a condition that interferes with body movement. The condition usually worsens over time. Research suggests that inflammation in certain areas of ...Phase
Interventional
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Safety and Efficacy of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)
This study is being done to learn more about AMG 570 in people with systemic lupus erythematosus (SLE). The purpose of the study is to ...Phase
Interventional
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Flexible Surface Coil for MRI
The purpose of this study is to test if we can use a redesigned device of the Magnetic Resonance Imaging (MRI) scanner, called a coil ...Phase
Interventional
