Displaying 102 (all) recruiting clinical trials.
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Autologous Intraarticular Micro-Fragmented Adipose Transfer
The purpose of this study is to determine if transferring fat tissue from your lower abdomen or outer thigh into the base of the thumb ...Phase
Interventional
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A Phase 2 Randomized Double-Blind Placebo-Controlled Efficacy and Safety Study of VIB7734 for the Treatment of Moderate to Severely Active Systemic Lupus Erythematosus
The purpose of this study is to learn how well VIB7734 is tolerated in patients with SLE, to determine if it causes any side effects ...Phase
Interventional
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A Multi-Center Randomized Double-blind Placebo-controlled Dose-finding Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CK-3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy
Some people with HCM have obstructive HCM (oHCM) and other participants have non-obstructive HCM (nHCM). HCM is a condition in which the heart muscle becomes ...Phase
Interventional
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A randomized double-blind placebo-controlled study of ALPN-101 in systemic lupus erythematosus.
Lupus is a disease that occurs when your body's immune system is active in a way that can injure your own healthy tissues and ...Phase
Interventional
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A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
If you or your child has been newly diagnosed with a brain tumor called Non-Germinomatous Germ Cell Tumor (NGGCT) there may be an opportunity to ...
Phase
Interventional
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Phase 2b Clinical Study Evaluating Efficacy and Safety of TAR-200 in Combination with Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants with High-Risk Non- Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin (BCG) who are Ineligible for or Elected Not to Undergo Radical Cystectomy
The purpose of the study is to determine the efficacy and safety of TAR-200 in combination with Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in participants ...Phase
Interventional
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A PHASE IB-II STUDY OF HIGH-DOSE POST-TRANSPLANT CYCLOPHOSPHAMIDE BORTEZOMIB AND ABATACEPT FOR THE PREVENTION OF GRAFT-VERSUS-HOST DISEASE (GVHD) FOLLOWING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)
The purpose of the study is to determine if the administration of the investigational prophylactic medications: PTCy, bortezomib and abatacept, for individuals with hematological malignancies ...
Phase
Interventional
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A Randomized Open-Label Phase 2 Study of a Patient-Specific Vaccine Targeting Neoantigens in Combination with Immune Checkpoint Blockade for Patients with Colon Cancer with Minimal Residual Disease Following Surgical Resection and Standard Adjuvant Chem
The purpose of the study is to determine the safety and effectiveness of the patient-specific-vaccine targeting neoantigens in combination with immune checkpoint blockade for patients ...
Phase
Interventional
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A Phase 2 Multicenter Double-Blind Randomized Placebo-controlled Study of Safety and Efficacy Of ANG-3070 in Patients with Primary Glomerular Disease and Persistent Proteinuria.
The purpose of this study is to see if an investigational drug, called ANG-3070, is safe and effective in kidney disease. ANG-3070 is considered investigational ...Phase
Non-Interventional
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A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Evinacumab in Patients with Severe Hypertriglyceridemia for the Prevention of Recurrent Acute Pancreatitis
The primary objective of the study is to determine the proportion of patients with elevated triglycerides (TG), without Familial Chylomicronemia Syndrome (FCS) due to loss ...Phase
Interventional
Accepts Healthy Volunteer
