Displaying 85 (all) recruiting clinical trials.
-
Induction Optimization with Stelara for Crohn s Disease
The purpose of this study is to compare the effectiveness of a second weight based dose of Stelara given intravenously to the standard dose administered ...Phase
Interventional
-
A randomized double-blind placebo-controlled study of ALPN-101 in systemic lupus erythematosus.
Lupus is a disease that occurs when your body's immune system is active in a way that can injure your own healthy tissues and ...Phase
Interventional
-
A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
If you or your child has been newly diagnosed with a brain tumor called Non-Germinomatous Germ Cell Tumor (NGGCT) there may be an opportunity to ...
Phase
Interventional
-
Phase 2b Clinical Study Evaluating Efficacy and Safety of TAR-200 in Combination with Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants with High-Risk Non- Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin (BCG) who are Ineligible for or Elected Not to Undergo Radical Cystectomy
The purpose of the study is to determine the efficacy and safety of TAR-200 in combination with Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in participants ...Phase
Interventional
-
A PHASE IB-II STUDY OF HIGH-DOSE POST-TRANSPLANT CYCLOPHOSPHAMIDE BORTEZOMIB AND ABATACEPT FOR THE PREVENTION OF GRAFT-VERSUS-HOST DISEASE (GVHD) FOLLOWING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT)
The purpose of the study is to determine if the administration of the investigational prophylactic medications: PTCy, bortezomib and abatacept, for individuals with hematological malignancies ...
Phase
Interventional
-
A phase 2 open-label single-arm cohort study to evaluate the safety efficacy and pharmacokinetics of sparsentan treatment in pediatric subjects with selected proteinuric glomerular diseases (EPPIK)
The purpose of this research study is to study if an investigational drug (one that is not FDA approved), named sparsentan, will help in the ...Phase
Interventional
-
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)
You can participate in this study if you are newly diagnosed with brain cancer (glioblastoma). The purpose of this study is to evaluate a peptide ...
Phase
Interventional
-
A Phase 2a Multicenter Randomized Double blind Study Evaluating the Efficacy and Safety of Subcutaneously Administered combination therapy in Improving the Signs and Symptoms in Participants with Active Psoriatic Arthritis.
The purpose of this study is to see if guselkumab and golimumab, when used together, are safe and effective for treating participants with active Psoriatic ...Phase
Interventional
-
A Randomized Double-blind Placebo controlled Multi-center 2-part Phase 2 Study to Evaluate Efficacy Safety and Tolerability of RGH-706 in Prader-Willi Syndrome
The hypothalamus is a small but complex part of the brain. It is an important regulator of body temperature, appetite, and hormone secretion. The hypothalamus ...Phase
Interventional
-
An Open-Label Study of CK-3773274 for Patients with Symptomatic Hypertrophic Cardiomyopathy (HCM)
HCM is a condition in which the heart muscle becomes abnormally thickened, which can sometimes block the blood flow out of the heart, and the ...Phase
Interventional
