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A Global Phase 2b Randomized Double-Blinded Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients with Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy FORTITUDE-HCM
The purpose of this study is to examine the effects of ninerafaxstat (an investigational drug) in people who are experiencing symptoms from their Non-Obstructive Hypertrophic ...Phase
Interventional
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An Open-label Multi-center Global Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects with Advanced Non-small Cell Lung Cancer (NSCLC)
This is a Phase 2 study testing different doses of a medicine called HLX43 for patients with advanced non-small cell lung cancer (NSCLC). HLX43 is ...
Phase
Interventional
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A Phase 2 Randomized Double-blind Placebo-controlled Parallel Study Evaluating the Safety and Efficacy of LB-P8 in Patients with Primary Sclerosing Cholangitis (PSC)
This main purpose of this placebo-controlled study to assess the safety and efficacy of LB-P8 in adult patients with Primary Sclerosing Cholangitis (PSC). The study ...Phase
Interventional
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A Phase IIb Randomized Double-blind Placebo-controlled Parallel Multidose Study to Evaluate the Efficacy Safety and PK of AZD0292 in Participants With Bronchiectasis and Chronic Pseudomonas aeruginosa Colonization
The purpose of this research is to learn more about an experimental drug, called AZD0292, including how safe it is, how long it stays in ...Phase
Interventional
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A Phase 2 Open-Label Study to Evaluate the Safety and Efficacy of Intravesical Instillation of TARA-002 in Adults with High-Grade Non-Muscle Invasive Bladder Cancer
Study TARA-002-101-Ph2 is an open-label Phase 2 study to investigate the safety and efficacy of TARA-002 administered intravesically in adults 18 years of age or ...Phase
Interventional
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A Phase 2a Randomized Double-blind Placebo-controlled Multiple-dose Crossover Study of the Effect of ZT-01 on Frequency of Nocturnal Hypoglycemia in Type 1 Diabetes Mellitus
The purpose of this research study is to assess the effect of ZT-01 (study treatment) on occurrence of night time (nocturnal) low blood sugar (hypoglycemia ...Phase
Interventional
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TITLE: TRIPL: Thoracic Radiotherapy and Inhibition of PD-1 and LAG-3 for Locally Advanced Non-Small Cell Lung Cancer
This is a Phase II study testing a new treatment for people with locally advanced non-small cell lung cancer (LA-NSCLC). The goal of this study ...
Phase
Interventional
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A multicenter trial utilizing ctDNA Guided Triplet Boost for Patients following treatment on nivolumab and relatlimab in patients with metastatic melanoma
Multi-site trial utilizing ctDNA measurements to guide first-line therapy choice for patients with advanced or metastatic melanoma.Phase
Interventional
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Multi-Center Randomized Double-Blind Placebo-Controlled Trial Comparing Standard of Care Adjuvant Temozolomide With or Without 5-Aminolevulinic Acid (5-ALA) With Concomitant Low Intensity Diffuse Ultrasound (LIDU) Sonodynamic Therapy (SDT) System In Patients With Newly Diagnosed Glioblastoma After Completion of Chemoradiotherapy
This is a study testing a new treatment for patients with newly diagnosed glioblastoma (GBM), a type of brain cancer, after they have had surgery ...
Phase
Interventional
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A Phase 2 Posology Study with Long-Term Extension in Participants with Well-Controlled Recurrent Pericarditis to Evaluate the Efficacy and Safety of Transition Regimens to KPL-387 Monotherapy from Standard Therapies
The purpose of this study is to see how well KPL-387 works for people who are currently taking medications for the treatment of recurrent pericarditis ...Phase
Interventional
