Displaying 85 (all) recruiting clinical trials.
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A novel Phase 2 double-blind randomized controlled clinical trial to evaluate the efficacy of centrally acting non-toxic ACE inhibition in cognitive impairment associated with SLE
This research study is being done to test the effects of centrally-acting ACE inhibitor, named lisinopril, on resting metabolism in the brain and on cognitive ... -
Interventional randomized double-blind parallel-group placebo-controlled multi-centre study to assess the efficacy safety and tolerability of Lu AF82422 in patients with Multiple System Atrophy
The purpose of this study is to find out whether a potential new treatment, the investigational drug Lu AF82422, is safe and effective in people ... -
A Phase 2 Study of BA3011 Alone and in Combination with Nivolumab in Adult Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) Who Had Prior Disease Progression on a PD-1/L-1 Inhibitor
The purpose of the study is designed to evaluate the efficacy and safety of BA3011 alone and in combination with nivolumab in patients with AXL-expressing ... -
Phase II Trial of Radium-223 Dichloride in Combination with Paclitaxel in Patients with Bone Metastatic Breast Cancer
The purpose of the study is to determine the safety and efficacy of the combination of Radium-223 dichloride and paclitaxel. We want to know if ... -
A Telehealth tDCS Approach to Decrease Cannabis Use: Towards Reducing Multiple Sclerosis Disability
The purpose of this study is to determine if transcranial direct current stimulation, or tDCS, can be used to treat cannabis use disorder (CUD) in ... -
A randomized double-blind placebo-controlled study of ALPN-101 in systemic lupus erythematosus.
Lupus is a disease that occurs when your body's immune system is active in a way that can injure your own healthy tissues and ... -
A Phase 2 Trial of Chemotherapy followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
If you or your child has been newly diagnosed with a brain tumor called Non-Germinomatous Germ Cell Tumor (NGGCT) there may be an opportunity to ...
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Phase 2b Clinical Study Evaluating Efficacy and Safety of TAR-200 in Combination with Cetrelimab TAR-200 Alone or Cetrelimab Alone in Participants with High-Risk Non- Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guerin (BCG) who are Ineligible for or Elected Not to Undergo Radical Cystectomy
The purpose of the study is to determine the efficacy and safety of TAR-200 in combination with Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in participants ... -
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)
You can participate in this study if you are newly diagnosed with brain cancer (glioblastoma). The purpose of this study is to evaluate a peptide ...
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A Phase 2a Multicenter Randomized Double blind Study Evaluating the Efficacy and Safety of Subcutaneously Administered combination therapy in Improving the Signs and Symptoms in Participants with Active Psoriatic Arthritis.
The purpose of this study is to see if guselkumab and golimumab, when used together, are safe and effective for treating participants with active Psoriatic ...