Displaying 85 (all) recruiting clinical trials.
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A Two Part Phase IIa/b Multicentre Randomised Double-Blind Placebo-Controlled Parallel Group Dose-ranging Study to Assess Efficacy Safety and Tolerability of the Combination of Zibotentan and Dapagliflozin and Dapagliflozin Monotherapy Versus Placebo in Participants with Cirrhosis with Features of Portal Hypertension
The main purpose of this study is to learn more about the effects of two drugs called zibotentan and dapagliflozin, in patients with liver disease ...Phase
Interventional
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Effectiveness and impact of counseling enhanced with electronic cigarettes for harm reduction in smokers with opioid use disorder
We are conducting a research study to compare the effectiveness of telehealth counseling plus electronic cigarettes VERSUS telehealth counseling plus nicotine replacement therapy (patches and ...Phase
Interventional
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A Phase 2 Open-label Study Evaluating Dosimetry Randomized Dose Optimization Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants with PSMA PET-Positive Castration-Resistant Prostate Cancer
This is a three-part study which includes biodistribution (Part 1), dose optimization (Part 2) to determine the optimal dose of Ac-225 rosopatamab tetraxetan to be ...Phase
Interventional
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A Phase 2 Study of Ipatasertib in Combination with Pembrolizumab for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck.
This study is focusing on whether adding a drug called ipatasertib combined with pembrolizumab can help patients with cancer stop their disease progression. Patients will ...
Phase
Interventional
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A Phase II Randomized Double-Blind Placebo-Controlled Study of Ensifentrine in Subjects with Non-Cystic Fibrosis Bronchiectasis
The purpose of this study is to evaluate the effect and safety of the treatment Ensifentrine on the occurrence of pulmonary exacerbations and on patient-reported ...Phase
Interventional
