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A 12-week randomized double-blind placebo-controlled trial investigating the effects of levetiracetam in early psychosis
The purpose of this study is to determine whether adding levetiracetam to usual medication treatment improves outcomes in early psychosis by protecting a part of ...Phase
Interventional
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Behavioral Economics Trial To Enhance Regulation of Blood Pressure (BETTER-BP)
The goal of this research study is to understand whether a lottery program implemented for 6 months can improve medication adherence, and consequently, systolic blood ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Phase 2 Study Comparing the Efficacy and Safety of Tirzepatide versus Placebo in Patients with Nonalcoholic Steatohepatitis (NASH)
This study will examen whether the investigational drug, tirzepatide, is safe and able to help study participants with nonalcoholic steatohepatitis (NASH). “Investigational” means that the ...Phase
Interventional
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MULTICENTER PHASE II NEOADJUVANT AND ADJUVANT STUDY OF ALECTINIB ENTRECTINIB OR VEMURAFENIB PLUS COBIMETINIB IN PATIENTS WITH STAGES I-III NON-SMALL CELL LUNG CANCER WITH ALK ROS1 NTRK OR BRAF V600E MOLECULAR ALTERATIONS
The purpose of the trial is to determine the efficacy and safety of drugs in patients with untreated non-small cell lung cancer (NSCLC) tumors. In ...Phase
Interventional
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A Phase 2 Study of BIO 300 in Patients with COVID-19
COVID-19 is caused by a virus that triggers inflammation of the lungs. This inflammation may damage the lungs and lead to scarring. This scarring causes ...Phase
Interventional
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Innovative Trial for Understanding the Impact of Targeted Therapies in NF2 (INTUITT-NF2)
The purpose of the study is to evaluate the biological activity of systemic therapies in people with Neurofibromatosis type 2 (NF2) related tumors. Tumor types ...Phase
Interventional
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ANBL1821: A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# 141913) in Children with Relapsed Refractory or Progressive Neuroblastoma
The purpose of the study is to determine how well irinotecan hydrochloride, temozolomide, and dinutuximab work with or without eflornithine in treating patients with neuroblastoma ...Phase
Interventional
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Alexion NEPH-202 Ravulizumab trial
The purpose of the study is to evaluate the safety and efficacy of the study treatment in participants with Lupus Nephritis (LN).This study involves ...Phase
Interventional
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Cannabidiol for Treating PTSD symptoms and Neurocognitive Impairment in PTSD and PTSD Comorbid with TBI: A Placebo-controlled RCT with Neuralcircuit centered Precision Medicine Prediction of Response
PTSD is a disorder where someone has difficulty recovering after a traumatic event. Symptoms may include nightmares or unwanted memories of the trauma, avoidance of ...Phase
Interventional
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INTREPId (INTermediate Risk Erection PreservatIon Trial): A Randomized Trial of Radiation Therapy and Darolutamide for Prostate Cancer
The purpose of the trial is to determine whether Darolutamide plus radiation therapy (RT) is non-inferior to gonadotropin releasing hormone (GnRH) agonist and bicalutamide plus ...Phase
Interventional
