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A Randomized Double-Blind Placebo-Controlled Study in Cat-Allergic Patients with Allergic Rhinitis Who Live with a Cat to Assess the Efficacy and Safety of Anti-Fel d 1 Antibodies during Natural Cat Exposure in the Home
The main purpose of this study is to find out whether an experimental study drug called REGN1908-1909 works to reduce nasal and/or eye allergy ...Phase
Interventional
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Rimegepant for the treatment of migraine (with or without aura) in children and adolescents
The main purpose of this study is to learn how well the study drug works and how safe the study drug is in children and ...Phase
Interventional
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Sleep for Stroke Management And Recovery Trial (Sleep SMART)
The purpose of the study is to examine if continuous positive airway pressure (CPAP) treatment may improve outcomes after stroke. CPAP might improve your physical ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Multi-Center Phase 3 Study to Determine the Efficacy and Safety of TG-C in Subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee
The purpose of this clinical research study is to investigate the safety and efficacy (how well something works) of a drug named TG-C to treat ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase III Multicenter Randomized Double-Blind Double-Dummy Study to Evaluate Safety and Efficacy of Ocrelizumab in Children and Adolescents with Relapsing-Remitting Multiple sclerosis (Operetta 2)
The study will evaluate the safety and efficacy of ocrelizumab compared with fingolimod in children and adolescents with Relapsing-Remitting Multiple sclerosis (RRMS) The purpose of ...Phase
Interventional
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A PHASE 3 MULTI-CENTER MULTI-NATIONAL RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED INDUCTION AND MAINTENANCE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CC-93538 IN ADULT AND ADOLESCENT SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS
The purpose of this study is to see if CC-93538 is safe and effective as a possible treatment for EoE. To do this, a comparison ...Phase
Interventional
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A Phase 3 Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Adults with Familial Chylomicronemia Syndrome
The purpose of this study is to test two different dose levels of ARO-APOC3 administered 4 times, 3 months apart in people with Familial Chylomicronemia ...Phase
Interventional
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AGCT1532 - Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours
The purpose of this study is to investigate the accelerated BEP in improving the safety and efficacy for patients with intermediate and poor-risk metastatic germ ...
Phase
Interventional
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A randomized double-blind phase III study comparing NIS793 in combination with gemcitabine and nab-paclitaxel versus placebo combined with gemcitabine and nab-paclitaxel for first line treatment of metastatic pancreatic ductal adenocarcinoma (mPDAC)
The purpose of the study is to evaluate the efficacy and safety of NIS793 in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel and placebo in ...Phase
Interventional
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A Randomized Controlled Pragmatic Phase 3b/4 Study of Baricitinib in Patients with Rheumatoid Arthritis
The purpose of this research study is to help determine the safety of a drug called baricitinib. Baricitinib is a type of medicine called a ...Phase
Interventional
