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I-SPY 2 TRIAL -Investigation of Serial Studies to Predict your Therapeutic Response with Imaging and Molecular Analysis 2
The I-SPY 2.2 study is a way to improve how we treat breast cancer. It uses a plan to test new treatments and find ...
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A Phase 3 Open-Label Randomized Multi-Center Study of DZD9008 versus Platinum-Based Doublet Chemotherapy as First-Line Treatment for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertion Mutation
This study is being conducted to determine how safe and effective a drug called DZD9008 is compared to standard chemotherapy in patients with locally advanced ... -
OPTIMICE-PCR: DE-ESCALATION OF THERAPY IN EARLY-STAGE TNBC PATIENTS WHO ACHIEVE PCR AFTER NEOADJUVANT CHEMOTHERAPY WITH CHECKPOINT INHIBITOR THERAPY
This study is for patients with early-stage triple-negative breast cancer who received a treatment called pembrolizumab (a medicine used to treat melanoma). Some patients will ... -
A Phase 3 Multi-center Randomized Withdrawal and Long-Term Extension Study of Ampreloxetine for the Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Participants with Multiple System Atrophy
The purpose of this research is to study whether an investigational drug, called ampreloxetine, works and how safe it is when taken over several months ... -
A Clinical Research Study for Children Teens and Young Adults Diagnosed With Dravet Syndrome The Skyline Study
The Skyline Study is a Phase 3 clinical research study of an investigational medication for children, teens, and young adults diagnosed with Dravet syndrome who ... -
Duration and Efficacy of Azstarys (serdexmethylphenidate and dexmethylphenidate) on Adult ADHD Symptoms and Executive Function In Early Evening
The purpose of this open-label treatment study is to extend the safety and efficacy evidence basis for Azstarys, a recently FDA approved ADHD product, in ... -
Safety and Efficacy of Empagliflozin in Hemodialysis (SEED)
The purpose of this research study is to explore the safety and efficacy of a drug called empagliflozin (EMPA) in reducing kidney and cardiovascular events ... -
Phase 3 study evaluating AMG 757 Tarlatamab for patients with Small Cell Lung Cancer
This study is for patients with small cell lung cancer (SCLC). They want to see if a new treatment called tarlatamab (an immunotherapy that might ... -
A Phase 3 Multicenter Randomized Open-Label Trial of Epcoritamab in Combination with R-CHOP compared to R-CHOP in Subjects with High-Risk Diffuse Large B-Cell Lymphoma
This is a study to see if a new medicine called epcoritamab (works by binding to CD3 and CD20 on cells, which brings T cells ...
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A Randomised Double-blind Placebo-controlled Multicentre Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With Non-cirrhotic Non-alcoholic Steatohepatitis (NASH) and Fibrosis Stages F2 and F3
This Phase 3 study is conducted to evaluate Lanifibranorin adults with NASH and liver fibrosis stage 2 or 3 and consists of 2 parts: Part ...