Displaying 99 (all) recruiting clinical trials.
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A Phase 3 Randomized Double-Blind Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Brepocitinib in Adults with Dermatomyositis
The purpose of this study is to measure clinical efficacy of oral brepocitinib compared with placebo in participants with dermatomyositis. -
A 52-week Double-blind Placebo-controlled Randomized Phase 3 study Intended to Determine the Effects of seladelpar on normalization of Alkaline phosphatase Levels in Subjects with Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid
The purpose of this study is to determine the effects of seladelpar on normalization of Alkaline Phosphatase Levels in Subjects with Primary Biliary Cholangitis (PBC ... -
PRESERVE Heart Study
The purpose of this study is to evaluate if Non-Ischemic Heart Preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS ... -
A Phase 3 Multi-Center Randomized Double-Blind Trial to Evaluate The Efficacy and Safety of Aficamten Compared To Placebo in Adults with Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
The purpose of this research study is to compare the effects of aficamten and placebo on health status and exercise capacity in participants with non-obstructive ... -
A Stepped-Care Approach to Treating Dental Fear: A Sequential Multiple Assignment Randomized Trial for Cognitive-Behavioral Treatment via Mobile App and Evidence-Based Collaborative Care
The purpose of this study is to compare an intervention for dental fear to the usual approach (i.e., whatever your/your child's dentist ... -
A PHASE III RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED STUDY EVALUATING ATEZOLIZUMAB AND BEVACIZUMAB WITH AND WITHOUT TIRAGOLUMAB IN PATIENTS WITH UNTREATED LOCALLY ADVANCED OR METASTATIC HEPATOCELLULAR CARCINOMA
This study is testing if a new treatment works for patients with hepatocellular carcinoma (HCC) that's either very advanced or has spread to other ...
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A Phase 3 Randomized Double-blind Active-Comparator-Controlled Clinical Study of Adjuvant MK-7684A (Vibostolimab with Pembrolizumab) Versus Adjuvant Pembrolizumab in Participants with High-risk Stage II-IV Melanoma (KEYVIBE-010)
This research study is for people who are 12 years of age or older and weigh at least 40 kg, and who have had surgery ...
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A Randomized Open-label Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician s Choice in Patients with Triple Negative Breast Cancer That Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy
This is a large global study for people with a type of breast cancer called triple-negative breast cancer (TNBC). It's happening in many hospitals ...
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A Phase 3 Randomized Double-Blind Placebo- and Active-Comparator- Controlled Clinical study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With High-Risk Stage II-IV Melanoma
This study wants to find out if a new treatment called V940, when used with pembrolizumab, has fewer side effects and is more effective than ...