Displaying 125 (all) recruiting clinical trials.
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AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs.Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
The purpose of the study is to minimize toxicity by reducing therapy while maintaining current survival rates in the treatment of pediatric, adolescent and young ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Study in Cat-Allergic Patients with Allergic Rhinitis Who Live with a Cat to Assess the Efficacy and Safety of Anti-Fel d 1 Antibodies during Natural Cat Exposure in the Home
The main purpose of this study is to find out whether an experimental study drug called REGN1908-1909 works to reduce nasal and/or eye allergy ...Phase
Interventional
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Rimegepant for the treatment of migraine (with or without aura) in children and adolescents
The main purpose of this study is to learn how well the study drug works and how safe the study drug is in children and ...Phase
Interventional
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Sleep for Stroke Management And Recovery Trial (Sleep SMART)
The purpose of the study is to examine if continuous positive airway pressure (CPAP) treatment may improve outcomes after stroke. CPAP might improve your physical ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Multi-Center Phase 3 Study to Determine the Efficacy and Safety of TG-C in Subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee
The purpose of this clinical research study is to investigate the safety and efficacy (how well something works) of a drug named TG-C to treat ...Phase
Interventional
Accepts Healthy Volunteer
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A Phase III Multicenter Randomized Double-Blind Double-Dummy Study to Evaluate Safety and Efficacy of Ocrelizumab in Children and Adolescents with Relapsing-Remitting Multiple sclerosis (Operetta 2)
The study will evaluate the safety and efficacy of ocrelizumab compared with fingolimod in children and adolescents with Relapsing-Remitting Multiple sclerosis (RRMS) The purpose of ...Phase
Interventional
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DASL-HiCaP: Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate (ANZUP1801). A randomised phase 3 double-blind placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation in very high risk clinically localised prostate cancer
The purpose of the study is to determine the effectiveness of darolutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinising hormone releasing ...Phase
Interventional
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A PHASE 3 MULTI-CENTER MULTI-NATIONAL RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED INDUCTION AND MAINTENANCE STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CC-93538 IN ADULT AND ADOLESCENT SUBJECTS WITH EOSINOPHILIC ESOPHAGITIS
The purpose of this study is to see if CC-93538 is safe and effective as a possible treatment for EoE. To do this, a comparison ...Phase
Interventional
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ACNS1931: A Phase 3 Study of Selumetinib (NSC# 748727 IND# 77782) or Selumetinib in Combination with Vinblastine for non-NF1 non-TSC Patients with Recurrent or Progressive Low-Grade Gliomas (LGGs) Lacking BRAFV600E or IDH1 Mutations
The purpose of the study is to determine and investigate the best dose of vinblastine in combination with selumetinib and the benefit of adding vinblastine ...
Phase
Interventional
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A Phase 3 Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Adults with Familial Chylomicronemia Syndrome
The purpose of this study is to test two different dose levels of ARO-APOC3 administered 4 times, 3 months apart in people with Familial Chylomicronemia ...Phase
Interventional
