Displaying 104 (all) recruiting clinical trials.
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A Phase 3 Randomized Multicenter Double-Blind Placebo-Controlled Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Placebo Plus Standard of Care in Mayo Stage IV Subjects with Light Chain (AL) Amyloidosis
The purpose of the study is to evaluate the efficacy of birtamimab plus standard of care compared to placebo plus standard of care in Mayo ...Phase
Interventional
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The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis (SAVVE) Study
The purpose of this study is to learn whether the Hancock Jaffe bioprosthetic venous valve(VenoValve®) will help subjects like you with severe chronic venous ...Phase
Interventional
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A multi-center randomized double-blind placebocontrolled parallel group phase III study to evaluate the efficacy and safety of LNP023 in primary IgA nephropathy patients
The purpose of the study is to find out if LNP023 (also called iptacopan) is safe and effective in people who have primary IgA Nephropathy ...Phase
Interventional
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Goal-Directed Cardiopulmonary Resuscitation in Cardiac Arrest Using a Novel Physiological Target: A Pilot Mechanistic Randomized Control Trial
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological ...Phase
Interventional
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A Phase 3b Multicenter Randomized Double-blind Placebo-controlled Study Evaluating the Efficacy and Safety of Subcutaneously Administered Guselkumab in Improving the Signs and Symptoms and Inhibiting Radiographic Progression in Participants with Activ
The purpose of this study is to see if guselkumab is safe and useful for treating patients with active psoriatic arthritis (PSA). Guselkumab is a ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Phase 3 Study of ISIS 678354 Administered Subcutaneously to Patients with Severe Hypertriglyceridemia
The purpose of this study is to see how safe and effective an investigational drug called ISIS 678354 is for people with severe hypertriglyceridemia. This ...Phase
Interventional
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NRG-BR007: A PHASE III CLINICAL TRIAL EVALUATING DE-ESCALATION OF BREAST RADIATION FOR CONSERVATIVE TREATMENT OF STAGE I HORMONE SENSITIVE HER2-NEGATIVE ONCOTYPE RECURRENCE SCORE = 18 BREAST CANCER
The purpose of the study is to determine and examine whether breast conservation surgery and endocrine therapy results in a non-inferior rate of ipsilateral-breast tumor ...
Phase
Interventional
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AGCT1531: A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs.Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
The purpose of the study is to minimize toxicity by reducing therapy while maintaining current survival rates in the treatment of pediatric, adolescent and young ...Phase
Interventional
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Rimegepant for the treatment of migraine (with or without aura) in children and adolescents
The main purpose of this study is to learn how well the study drug works and how safe the study drug is in children and ...Phase
Interventional
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Sleep for Stroke Management And Recovery Trial (Sleep SMART)
The purpose of the study is to examine if continuous positive airway pressure (CPAP) treatment may improve outcomes after stroke. CPAP might improve your physical ...Phase
Interventional
