Displaying 125 (all) recruiting clinical trials.
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Prospective Randomized Controlled Blinded Pivotal Study in Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) at One or Two Levels Using Infuse Bone Graft and The Capstone Spinal System with Posterior Supplemental Fixation for the Trea
The purpose of this study is to evaluate the use of Infuse™ Bone Graft in combination with the Capstone™ Spinal System and other hardware in ...Phase
Interventional
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A Phase 3 Randomized Double- Or Observer-Blinded Placebo-Controlled Trial to Evaluate the Efficacy and Safety of a Respiratory Syncytial Versus (RSV) Prefusion F Subunit Vaccine in Infants Born To Women Vaccinated During Pregnancy
The purpose of this study is to find out if Pfizer’s investigational RSVpreF vaccine prevents the development of RSV illness in your baby. A ...Phase
Interventional
Accepts Healthy Volunteer
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Statins Use in Intracerebral Hemorrhage Patients
This research is being done to find out if it is better to continue or discontinue statin drugs in people who have recently had a ...Phase
Interventional
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A phase 3 randomized trial for patients with de novo AML comparing standard therapy including gemtuzumab ozogamicin GO to CPX-351 with GO and the addition of the FLT3 inhibitor gilteritinib for patients with FLT3 mutations
The purpose of the study is to compare standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia ...Phase
Interventional
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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly
Fetal complete (i.e., third degree) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally ...Phase
Interventional
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A Phase 3 Randomized Double-blind Matching Placebo-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) versus CRT Alone in Participants with MIBC (KEYNOTE-992)
The purpose of the study is to determine the safety and efficacy of Pembrolizumab (MK-3475) and Chemoradiotherapy (CRT) for people who have muscle-invasive bladder cancer ...Phase
Interventional
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A Phase 3 Randomized Open-Label Three Arm Study of PF-06801591 in Combination with BCG (Induction With or Without Maintenance) Versus BCG (Induction and Maintenance) in Participants with HR BCG-Na ve NMIBC (B8011006)
The purpose of the study is to determine the safety and efficacy of PF-06801591 (an anti-PD-1 antibody) combined with Bacillus Calmette- Guerin (BCG) in patients ...Phase
Interventional
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A Multicenter Randomized Double-Blind Parallel Group Placebo-Controlled Trial to Evaluate the Effect of InHospital Initiation of Dapagliflozin on Clinical Outcomes in Patients with Heart Failure with Reduced Ejection Fraction Who Have Been Stabilized During Hospitalization for Acute Heart Failure
This study will test whether the drug dapagliflozin is safe and has beneficial effects when added to conventional heart failure therapy in patients who have ...Phase
Interventional
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A Double-Blind Randomized Placebo-Controlled Study and Open-Label Long Term Extension of study drug in Patients with Primary Biliary Cholangitis with Inadequate Response or Intolerance to Ursodeoxycholic Acid
The main purpose is to study the effect of daily oral administration of 80 mg elafibranor on cholestasis (impairment of bile formation and/or bile ...Phase
Interventional
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STAMP: Surgically Treated Adjuvant Merkel cell Carcinoma with Pembrolizumab a Phase III Trial (ECOG EA6174)
This phase III trial studies how well pembrolizumab works compared to standard of care observation in treating patients with stage I-III Merkel cell cancer that ...Phase
Interventional
