Displaying 97 (all) recruiting clinical trials.
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An INS1007 Phase III program in Non Cystic Fibrosis Bronchiectasis
The purpose of this study is to evaluate the efficacy, safety, and tolerability of brensocatib as treatment for non-cystic fibrosis bronchiectasis (NCFBE). Brensocatib is an ...Phase
Interventional
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ENCORE - A Randomized Double-Blind Placebo-Controlled Active Comparator Multicenter Study to Evaluate the Efficacy and Safety of an Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) treatment on patient-reported symptoms in patients newly ...Phase
Interventional
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AALL1631: International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ ALL Testing Imatinib in Combination with Two Different Cytotoxic Chemotherapy Backbones
The purpose of the study is to determine how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive ...Phase
Interventional
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Phase 3 trial of oral ALZ-801 in Early AD patients who are homozygous for the epsilon 4 variant of the Apolipoprotein E gene (APOE4/4)
The purpose of this study is to determine if the study drug called ALZ-801 is safe, if it is well tolerated (how your body reacts ...Phase
Interventional
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Phase 3 Clinical Trial in Adult Growth Hormone Deficiency with TransCon hGH
The primary objective of this trial is to assess the efficacy of once-weekly lonapegsomatropin compared to placebo in adults with growth hormone deficiency (GHD). The ...Phase
Interventional
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A Phase 3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients with Autosomal Dominant Polycystic Kidney Disease
The study will examine if bardoxolone methyl, a drug being developed by Reata Pharmaceuticals, can improve autosomal dominant polycystic kidney disease (ADPKD), with its disease-modifying ...Phase
Non-Interventional
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A Randomized Controlled Trial to compare the effectiveness of Fecal Microbiota Transplantation (FMT) in combination with Bezlotoxumab compared to FMT and placebo for the prevention of CDI recurrence in patients with Inflammatory Bowel Disease and Recurrent Clostridium difficile Infection
This study will find out if fecal microbiota transplantation (also known as FMT) paired with Bezlotoxumab compared to FMT and placebo is a better treatment ...Phase
Interventional
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Optimizing Retention Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
This multicenter study seeks to better evaluate treatment strategies for the management of opioid use disorder – it aims to improve treatment outcomes for both patients ...Phase
Interventional
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ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)
The purpose of this research study is to evaluate the long-term safety and tolerability of seladelpar in treating PBC patients. Primary Biliary cholangitis (PBC) is ...Phase
Interventional
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CAreful Ventilation In COVID 19-induced ARDS - The CAVIARDS 19 Trial
ARDS is a severe form of lung injury which makes breathing very difficult and limits the ability of the respiratory system to provide oxygen to ...Phase
Interventional
