Displaying 131 (all) recruiting clinical trials.
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A Phase 2 Randomized Double-Blind Study to Evaluate the Efficacy Safety and Tolerability of Different Veverimer Dose Regimens in Adults with CKD and Metabolic Acidosis
The objective of this 26-week study is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and ...Phase
Interventional
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Tensi+ for treating Overactive Bladder: A 2 Randomized Controlled Trial
The purpose of this study is to investigate the safety and efficacy of the device Tensi+ in reducing symptoms of overactive bladder (OAB), such as ...Phase
Interventional
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A Phase III Multicentre Randomised Open-label Study to Compare the Efficacy and Safety of AZD0486 plus Rituximab versus Chemotherapy plus Rituximab in Previously Untreated Participants with Follicular Lymphoma (SOUNDTRACK-F1)
This is a Phase III study testing a new treatment for people with untreated follicular lymphoma (FL). The study will compare surovatamig combined with rituximab ...
Phase
Interventional
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C1091009-A Study to Learn About Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Infants
The purpose of this study is to learn about the safety and how the group B streptococcus (GBS) vaccine works in pregnant women and their ...Phase
Interventional
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ALN-TTRSC04-004: TRITON-PN: A Phase 3 Global Randomized Open-Label Study to Evaluate the Efficacy and Safety of Nucresiran in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Polyneuropathy (hATTR-PN)
The purpose of this study is to investigate the safety and efficacy of nucresiran compared to vutrisiran in patients with hereditary ATTR amyloidosis with polyneuropathy ...Phase
Interventional
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Phase III Randomized Open-label Global Multicenter Study of Rilvegostomig or Durvalumab in Combination With Chemotherapy as a First-line Treatment for Patients With Advanced Biliary Tract Cancer (Artemide Biliary 02)
This is a Phase III study that is taking place at hospitals and medical centers around the world. The study is testing whether a new ...
Phase
Interventional
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A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults
The purpose of this study is to learn more about the safety and effectiveness of the RSV vaccine in immunocompromised individuals. Researchers also hope to ...Phase
Interventional
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An Open-Label Randomized Multicenter Phase 3 Study Investigating the Efficacy and Safety of BGB-43395 Plus Letrozole versus CDK4/6 Inhibitors (Abemaciclib Palbociclib Ribociclib) Plus Letrozole in Patients with Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Systemic Anticancer Treatment for Advanced or Metastatic Disease
This is a Phase 3 study comparing BGB-43395 plus letrozole with the current standard treatment of an approved CDK4/6 inhibitor (abemaciclib, palbociclib, or ribociclib ...
Phase
Interventional
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A Phase III Open-Label Randomised Multicentre Study of Consolidation with a Single Administration of AZD0120 a Dual-Targeting Autologous Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against BCMA and CD19 Compared with Continuous Standard Therapy in Participants with NDMM Who Are Ineligible to Receive ASCT as Initial Therapy (DURGA-5)
This is a Phase III, randomized, multicenter, open-label study in people with newly diagnosed multiple myeloma (NDMM) who cannot receive an autologous stem cell transplant ...
Phase
Interventional
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A Phase 3 Multicenter Randomized Open-label Trial of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy With or Without Radiotherapy as Adjuvant Treatment for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
This is a Phase III study testing T-DXd (Enhertu) as a treatment after surgery for people with HER2-expressing endometrial cancer. The study will compare T-DXd ...
Phase
Interventional
