Displaying 101 (all) recruiting clinical trials.
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SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this program is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs and ...Phase
Interventional
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A Phase 3 Superiority Study Comparing the Safety and Efficacy of SNP-ACTH (1-39) Gel compared to Rituximab and FDA approved biosimilars in Adults with Primary Membranous Nephropathy (PMN) in a Two-Phase Adaptive Trial Design
This trial is recruiting individuals with Primary Membranous Nephropathy (PMN) - a kidney-specific, autoimmune disease in which your body's defense system turns against you and ...Phase
Interventional
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SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this research study is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs ...Phase
Interventional
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A Prospective Multicenter Randomized Two-Arm Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch Sirolimus-Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis (MAGICAL ISR)
The treatment for narrowed or blocked arteries often involves stents, which are inserted into heart blood vessels to alleviate blockages. Drug-eluting stents (DES) release medication ...Phase
Interventional
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WA43966: A Phase III Multicenter Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of RO7434656 An Antisense Inhibitor of Complement Factor B in Patients with Primary IgA Nephropathy at High Risk of Progression
The purpose of this study is to compare the safety and effects of RO7434656 versus placebo in participants with IgAN. In this study, you will ...Phase
Interventional
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A Phase 3 Randomized Double-Blind Multicenter Study to Evaluate the Efficacy Safety and Tolerability of Psilocybin in Adults with Major Depressive Disorder
The purpose of this research study is to see if the investigational drug, psilocybin, can help people with major depressive disorder (MDD). This clinical trial ...Phase
Interventional
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A Phase III Randomized Double-blind Placebo-controlled Multicenter Trial to Evaluate the Efficacy and Safety of Diamyd to Preserve Endogenous Beta Cell Function in Adolescents and Adults with Recently Diagnosed Type 1 Diabetes Carrying the Genetic HLA DR3-DQ2 Haplotype
The purpose of this study is to test the safety and effectiveness of an investigational drug called Diamyd®. Diamyd® is considered “investigational” in this research ...Phase
Interventional
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Multicenter Adaptive Randomized Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections(STRIVE)
We are studying an investigational drug for treatment of people in the hospital with COVID-19. This drug is investigational because it can only be used ...Phase
Interventional
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A randomized double-blind double-dummy parallel-group study comparing the efficacy and safety of remibrutinib versus teriflunomide in participants with relapsing multiple sclerosis followed by extended treatment with open-label remibrutinib
The purpose of this research study is to compare remibrutinib and teriflunomide safety and efficacy in patients with relapsing forms of Multiple Sclerosis (RMS).Phase
Interventional
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LTI-401 An Open-Label Prospective Multicenter Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in Pulmonary Hypertension ASCENT
The purpose of this research study is to evaluate the long-term safety and tolerability of LIQ861 in patients with pulmonary hypertension (elevated pressure in your ...Phase
Interventional
