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Paroxysmal nocturnal hemoglobinuria (PNH) Registry
This is a non interventional registry to gather information on the clinical presentation and outcomes of patients with PNH. The PHN Registry will capture post-marketing ...Phase
Non-Interventional
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ClotTriever/CLOUT Registry Study
The purpose of the study is to collect information about how the ClotTriever Thrombectomy System (referred to as “ClotTriever”) works when treating deep vein thrombosis ...Phase
Interventional
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Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
The purpose of this research study is to see the short-term and long-term effects of topiramate on alcohol dependence comorbid (co-occurring) with post-traumatic stress disorder ...Phase
Interventional
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A Post-Market Clinical Evaluation of the Treatment of Femur Fractures with the Femoral Nail Piriformis Fossa (PF) of the T2 Alpha Femur Antegrade GT/PF Nailing System
The purpose of this study is to show the safety and performance of the T2 Alpha Femur Antegrade Piriformis Fossa (PF) Nail. Participants who will ...Phase
Interventional
Accepts Healthy Volunteer
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A Post-Market Clinical Evaluation of the Treatment of Femur Fractures with the Femoral Nail Greater Trochanter (GT) of the T2 Alpha Femur Antegrade GT/PF Nailing System
The purpose of this study is to show the safety and performance of the T2 Alpha Femur Antegrade Greater Trochanter (GT) Nail. Participants will be ...Phase
Interventional
Accepts Healthy Volunteer
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Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adults
This study seeks to meaningfully address the U.S. opioid epidemic by comparing the effectiveness of two medications used to treat opioid use disorder, extended-release ...Phase
Interventional
Accepts Healthy Volunteer
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Prospective observational registry for cystinuria patients on Thiola EC therapy
The purpose of this research study is to follow patients on Thiola EC for two years and collect cystinuria related treatment information in order to ...Phase
Interventional
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DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
Aspirin is commonly used to prevent heart attacks and strokes in clinical care. Commonly a “baby” aspirin (81mg) is prescribed for this purpose. However, higher ...Phase
Interventional
Accepts Healthy Volunteer
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Observational Study Assessing for Effect of CREON on Symptoms of Exocrine Pancreatic Insufficiency (EPI) in Patients with EPI due to Chronic Pancreatitis (CP)
The purpose of the study is collecting information on the effect of CREON on the symptoms of exocrine pancreatic insufficiency. The research explained below deals ...Phase
Non-Interventional
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Preventing Arthritis in a Multi-Center Psoriasis At-Risk Cohort (Multi-Center PAMPA Study)
Patients with psoriasis (PsO) are at a higher risk of developing psoriatic arthritis (PsA). About 1 in 3 patients with PsO will develop arthritis of ...Phase
Interventional
