Displaying 16 (all) recruiting clinical trials.
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PNH Registry
Alexion Pharmaceuticals, Inc. has been the Sponsor of a global PNH Registry since August 2004 and enrolling patients with PNH worldwide. The primary aim of ...Phase
Non-Interventional
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Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
The proposed study is a double-blind, 2-group randomized controlled trial designed to contrast acute and persisting effects of topiramate to those of placebo treatment in ...Phase
Interventional
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T2 Alpha Femur Antegrade PF
This investigation is a prospective, multicenter clinical investigation designed to examine the safety and efficacy/performance of the Femoral Nail PF of the T2 Alpha ...Phase
Interventional
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A Post-Market Clinical Evaluation of the Treatment of Femur Fractures with the Femoral Nail Greater Trochanter (GT) of the T2 Alpha Femur Antegrade GT/PF Nailing System
This prospective, multi-center, clinical investigation, designed to examine the safety and efficacy/performance of the Femoral Nail GT of the T2 Alpha Femur Antegrade GT ...Phase
Interventional
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DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
This study employs a placebo-controlled randomized cross-over design to investigate the impact of body weight and aspirin dose on levels of specialized pro-resolving lipid mediators ...Phase
Interventional
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Preventing Arthritis in a Multi-Center Psoriasis At-Risk Cohort (Multi-Center PAMPA Study)
This is a multi-center (North-America), randomized, double-blind, placebo-controlled, wait-list, interventional, preventive trial of guselkumab in high-risk psoriasis patients compared to non-biologic standard of care. Population ...Phase
Interventional
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Depression treatment and A dynamics: A study of Alzheimer s disease risk (ABD Study)
The study will use a randomized 8-week double-blind placebo controlled parallel trial using escitalopram to test the associations between depressive symptoms (captured by the MADRS ...Phase
Interventional
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Predicting poor vaccine responders to Hepatitis B vaccination
Hepatitis B vaccines are indicated broadly for the prevention of hepatitis B infection, yet the vaccine is not uniformly effective in all individuals. We need ...Phase
Interventional
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LONG-TERM FOLLOW-UP STUDY OF PATIENTS WITH SPINAL MUSCULAR ATROPHY RECEIVING RISDIPLAM TREATMENT
This study will evaluate the long-term safety and effectiveness of risdiplam (Evrysdi?), prescribed on the basis of the U.S. Package Insert (USPI) and clinician ...Phase
Non-Interventional
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Randomized Controlled Open-Label Parallel Group Multi-Center Prospective Phase 4 Study Comparing the Efficacy of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2 3 and 4 Pressure Injuries
This post-marketing study is being performed to assess the effectiveness of Altrazeal® Transforming Powder Dressing (“Altrazeal®” or “TPD”) manufactured by ULURU Inc. in patients with ...Phase
Interventional
