Displaying 20 (all) recruiting clinical trials.
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A Multi-center Open-label Single-arm Phase 2/3 Trial Evaluating the Safety and Pharmacokinetics of Calaspargase Pegol for Treatment of Adults Aged 22 To >65 Years with Newly-diagnosed Philadelphia-negative ALL
The purpose of the study is to optimize the dosage of calaspargase pegol in newly-diagnosed Philadelphia-negative acute lymphoblastic leukemia (ALL) patients based on age. We ...Phase
Interventional
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An Open Label Long-term Extension study to investigate the safety of PF-06823859 Administered to Adult Participants with Active Dermatomyositis (C0251008)
The purpose of this study (C0251008) is to evaluate the long-term safety, and effectiveness of PF06823859 (active study drug) in adult participants with dermatomyositis (DM ...Phase
Interventional
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Targeting Hyaluronan Accumulation Through Exercise in T2DM
The purpose of this study is to examine the effects of exercise on hyaluronan (HA) accumulation in calf muscles. HA is seen in skeletal muscle ...Phase
Interventional
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A Multicenter Randomized Double-Blind Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn s Disease
The purpose of this study is to assess an investigational drug called etrasimod (also referred to as the “study drug”) in the treatment of Crohn ...Phase
Interventional
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A Phase 2/3 Randomized Open-Label Study of Maintenance GRT-C901/GRT-R902 A Neoantigen Vaccine in Combination with Immune Checkpoint Blockade for Patients with Metastatic Colorectal Cancer
The purpose of the study is to demonstrate clinical efficacy and characterize the clinical activity relating to the maintenance therapy with GRT-C901/GRT-R902 in combination ...Phase
Interventional
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The use of cannabidiol (CBD) in pain reduction for knee osteoarthritis. A Double-Blind Randomized Control Study
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain needed in people with knee osteoarthritis. CBD ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects at Risk of Pulmonary Hypertension associated with Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2)
The purpose of this study is to determine if the study drug, inhaled nitric oxide (iNO), when given and breathed through an investigational study device ...Phase
Interventional
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NRG-GI008: COLON ADJUVANT CHEMOTHERAPY BASED ON EVALUATION OF RESIDUAL DISEASE (CIRCULATE-US)
You can participate in this study if you are diagnosed with stage 2 or stage 3 colon cancer. The purpose of this study is to ...
Phase
Interventional
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Presence or Absence of blood in the GI lumen Correlating a HemoPill acute measurement with a subsequent endoscopic finding
The HemoPill acute is a swallowable capsule device that has the capability to detect blood in the upper digestive tract. Bleedings in the upper digestive ...Phase
Interventional
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Assessment of the Efficacy Safety and Pharmacokinetics of Orally Administered Epetraborole in Patients with Treatment-refractory Mycobacterium avium Complex Lung Disease
The purpose of this study is to learn about the effects of a study medicine, Epetraborole, to assess the efficacy for treating refractory MAC, to ...Phase
Interventional
