Displaying 13 (all) recruiting clinical trials.
-
i-Matter: Investigating an mHealth texting tool for embedding patient-reported data into diabetes management
This study has two phases that will be completed over the course of 5 years. Phase 1 consists of the following: (1) focus groups to ...Phase
Interventional
-
AHEP1531: Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)
This trial is the first international cooperative liver tumors trial in which a consensus approach was established by investigators representing Children’s Oncology Group (COG ...Phase
Interventional
-
Site for Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck
The purpose of the study is to determine whether docetaxel alone is as active as docetaxel and cetuximab combination and whether either taxane-based regimen is ...Phase
Interventional
-
A Randomized Open-Label Phase 2/3 Study Comparing Cobolimab + Dostarlimab+Docetaxel to Dostarlimab+Docetaxel to Docetaxel Alone in Participants with Advanced Nonsmall Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy (Costar Lung)
The purpose of the study is to compare cobolimab and dostarlimab and docetaxel to dostarlimab and docetaxel to docetaxel alone for safety, efficacy, and tolerability ...Phase
Interventional
-
A Multi-center Open-label Single-arm Phase 2/3 Trial Evaluating the Safety and Pharmacokinetics of Calaspargase Pegol for Treatment of Adults Aged 22 To >65 Years with Newly-diagnosed Philadelphia-negative ALL
The purpose of the study is to optimize the dosage of calaspargase pegol in newly-diagnosed Philadelphia-negative acute lymphoblastic leukemia (ALL) patients based on age. We ...Phase
Interventional
-
An Open Label Long-term Extension study to investigate the safety of PF-06823859 Administered to Adult Participants with Active Dermatomyositis (C0251008)
The purpose of this study (C0251008) is to evaluate the long-term safety, and effectiveness of PF06823859 (active study drug) in adult participants with dermatomyositis (DM ...Phase
Interventional
-
Targeting Hyaluronan Accumulation Through Exercise in T2DM
The purpose of this study is to examine the effects of exercise on hyaluronan (HA) accumulation in calf muscles. HA is seen in skeletal muscle ...Phase
Interventional
-
A Multicenter Randomized Double-Blind Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn s Disease
The purpose of this study is to assess an investigational drug called etrasimod (also referred to as the “study drug”) in the treatment of Crohn ...Phase
Interventional
-
A Phase II/III randomized study of R-miniCHOP with or without oral azacitidine (CC-486) in participants age 75 years or older with newly diagnosed diffuse large B cell lymphoma Grade IIIb Follicular Lymphoma transformed lymphoma and high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements
The purpose of the study is to evaluate the study drug CC-486 (oral azacitidine) plus the standard drug therapy that fights cancer cells for patients ...Phase
Interventional
-
Presence or Absence of blood in the GI lumen Correlating a HemoPill acute measurement with a subsequent endoscopic finding
The HemoPill acute is a swallowable capsule device that has the capability to detect blood in the upper digestive tract. Bleedings in the upper digestive ...Phase
Interventional
