Clinical Trials and Research Studies

At NYU Langone Health, our doctors and researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.

Recently Added/Updated Trials

  • A Phase I/IIa Open-label Multi-centre Study to Assess the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of AZD0022 Monotherapy and in Combination with Anti-cancer Agents in Participants with Tumours Harbouring a KRASG12D Mutation (ALAFOSS-01)

    This study is a trial to test the tolerability, side effects, and early effectiveness of the drug AZD0022 in patients with advanced tumors that have ...

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  • A Phase 1 Randomized Observer-Blind Study to Evaluate the Safety And Tolerability of a Vaccine Candidate Against Respiratory Syncytial Virus in Healthy Individuals 18 Through 49 Years of Age

    The purpose of this study is to see if a new type of investigational Respiratory Syncytial Virus (RSV) vaccine called “modRNA RSV vaccine” is safe ...

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  • A Phase 1b Study of JNJ-78278343 a T-cell Redirecting Agent Targeting Human Kallikrein 2 (KLK2) in Combination with either JNJ-63723283 (cetrelimab) Taxane Chemotherapy or Androgen Receptor Pathway Inhibitors for Metastatic Castration- Resistant Prostate Cancer

    This study will test the early effects of the immunotherapy drug JNJ-78278343, a bispecific antibody targeting KLK2 and CD3, combined with taxane chemotherapy or androgen ...

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  • DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study

    Type 2 Diabetes (T2D) is a medical condition in which high blood sugars develop in the body. The DISCOVERY study team is doing this study ...

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  • A pivotal prospective open-label multi-center study of safety and effectiveness of cochlear implantation in an expanded population of adults with bilateral sensorineural hearing loss

    The purpose of this research study is to examine the safety and effectiveness of cochlear implantation (CI) in an expanded population of adults who do ...

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  • A Multicenter Randomized Double-Blind Parallel-Group Dose-Controlled Study Evaluating the Safety and Efficacy of RE104 for Injection in the Treatment of Patients with Postpartum Depression (PPD)

    The purpose of collecting your pregnancy information is to see if RE104 has any effects on pregnancy, its outcome, and the birth and health of ...

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  • Autonomic dysfunction and peripheral neuropathy in patients with cardiac ATTR amyloidosis

    This study will aim to determine the most reliable and cost-efficient studies for diagnosing peripheral polyneuropathy and autonomic neuropathy in patients with ATTR amyloidosis who ...

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  • EVEREST-2: A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B694 an Autologous Logic-gated Tmod CAR T in Heterozygous HLA-A*02 Adults with Recurrent Unresectable Locally Advanced or Metastatic Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

    econditioning lymphodepletion) for different cancers that express mesothelin (MSLN). First, the study team will test it on a small number of patients to see if ...

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