Clinical Trials and Research Studies

At NYU Langone Health, our doctors and researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.

Recently Added/Updated Trials

  • An Open-label Phase 1 Multicenter Study to Evaluate the Safety and Preliminary Anti-tumor activity of NT-112 in Human Leukocyte Antigen-C*08:02-Positive Adult Subjects with Unresectable Advanced and/or Metastatic Solid Tumors That Are Positive for the KRAS G12D Mutation

    This study is testing a NT-112, a type of cellular therapy, in patients with advanced cancer, such as lung, pancreatic, or colorectal cancer, who have ...

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  • Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects with Advanced or Metastatic Solid Tumors

    This is study is testing a new medicine called AFNT-211 for patients with advanced or metastatic (cancer that has spread) that has specific genetic markers ...

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  • A PHASE 1B/2 MULTICENTER OPEN-LABEL STUDY OF IFINATAMAB DERUXTECAN (I-DXd) A B7-H3 ANTIBODY-DRUG CONJUGATE (ADC) IN COMBINATION WITH ATEZOLIZUMAB WITH OR WITHOUT CARBOPLATIN AS FIRST-LINE INDUCTION OR MAINTENANCE IN SUBJECTS WITH EXTENSIVE-STAGE SMALL CELL LUNG CANCER (ES-SCLC) (IDeate-Lung03)

    This global study is designed to test how safe and effective the drug I-DXd is when combined with atezolizumab, with or without carboplatin. The treatment ...

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  • The IRIS trial: A clinical trial for people living with active lupus nephritis (LN)

    IRIS is looking to see if a new FDA-approved therapy called SAPHNELO® may be effective in treating people with active LN. SAPHNELO® is the brand ...

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  • A Study to Evaluate PF-06823859 in People With Active Idiopathic Inflammatory Myopathies (Including Dermatomyositis or Polymyositis)

    The purpose of this research study is to learn about the effects of the study drug PF-06823859 for treating dermatomyositis (DM) or polymyositis (PM).

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  • A Phase 1/2 Study to Evaluate the Safety and Efficacy of AZD0486 in Adolescent and Adult Participants with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukaemia

    This study is designed to test how effective a new drug called AZD0486 (BITE for CD19) is for patients relapsed/refractory B-cell acute lymphoblastic leukemia ...

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  • A Phase I/IIa Open-label Multi-centre Study to Assess the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of AZD0022 Monotherapy and in Combination with Anti-cancer Agents in Participants with Tumours Harbouring a KRASG12D Mutation (ALAFOSS-01)

    This study is a trial to test the tolerability, side effects, and early effectiveness of the drug AZD0022 in patients with advanced tumors that have ...

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  • A Phase 1 Randomized Observer-Blind Study to Evaluate the Safety And Tolerability of a Vaccine Candidate Against Respiratory Syncytial Virus in Healthy Individuals 18 Through 49 Years of Age

    The purpose of this study is to see if a new type of investigational Respiratory Syncytial Virus (RSV) vaccine called “modRNA RSV vaccine” is safe ...

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